CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030685
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Beta-catenin-like protein 1 
Protein Synonyms/Alias
 cDNA FLJ53492, highly similar to Beta-catenin-like protein 1 
Gene Name
 CTNNBL1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
305SNRERFLKGEGLQLMubiquitination[1, 2]
328ISRSSALKVLDHAMIubiquitination[2]
345EGTDNCHKFVDILGLubiquitination[2]
361TIFPLFMKSPRKIKKubiquitination[2]
368KSPRKIKKVGTTEKEubiquitination[2]
402QRTRLLNKFTENDSEubiquitination[2]
410FTENDSEKVDRLMELubiquitination[2]
430GAMQVADKKIEGEKHacetylation[3]
430GAMQVADKKIEGEKHubiquitination[2]
431AMQVADKKIEGEKHDubiquitination[2]
500NMRGSSIKIVRHIIKacetylation[4]
500NMRGSSIKIVRHIIKubiquitination[2]
507KIVRHIIKEYAENIGacetylation[3]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 536 AA 
Protein Sequence
MRRKQTGTRE RGRYREEEMT VVEEADDDKK RLLQIIDRDG EEEEEEEEPL DESSVKKMIL 60
TFEKRSYKNQ ELRIKFPDNP EKFMESELDL NDIIQEMHVV ATMPDLYHLL VELNAVQSLL 120
GLLGHDNTDV SIAVVDLLQE LTDIDTLHES EEGAEVLIDA LVDGQVVALL VQNLERLDES 180
VKEEADGVHN TLAIVENMAE FRPEMCTEGA QQGLLQWLLK RLKAKMPFDA NKLYCSEVLA 240
ILLQDNDENR ELLGELDGID VLLQQLSVFK RHNPSTAEEQ EMMENLFDSL CSCLMLSSNR 300
ERFLKGEGLQ LMNLMLREKK ISRSSALKVL DHAMIGPEGT DNCHKFVDIL GLRTIFPLFM 360
KSPRKIKKVG TTEKEHEEHV CSILASLLRN LRGQQRTRLL NKFTENDSEK VDRLMELHFK 420
YLGAMQVADK KIEGEKHDMV RRGEIIDNDT EEEFYLRRLD AGLFVLQHIC YIMAEICNAN 480
VPQIRQRVHQ ILNMRGSSIK IVRHIIKEYA ENIGDGRSPE FRENEQKRIL GLLENF 536 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR013180; DUF1716_euk. 
Pfam
 PF08216; DUF1716 
SMART
  
PROSITE
  
PRINTS