CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044339
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Methyltransferase-like protein 4 
Protein Synonyms/Alias
  
Gene Name
 METTL4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
388ILGRVQEKTALPLRGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 419 AA 
Protein Sequence
MSVVHQLSAG WLLDHLSFIN KINYQLHQHH EPCCRKKEFT TSVHFESLQM DSVSSSGVCA 60
AFIASDSSTK PENDDGGNYE MFTRKFVFRP ELFDVTKPYI TPAVHKECQQ SNEKEDLMNG 120
VKKEISISII GKKRKRCVVF NQGELDAMEY HTKIRELILD GSLQLIQEGL KSGFLYPLFE 180
KQDKGSKPIT LPLDACSLSE LCEMAKHLPS LNEMEHQTLQ LVEEDTSVTE QDLFLRVVEN 240
NSSFTKVITL MGQKYLLPPK SSFLLSDISC MQPLLNYRKT FDVIVIDPPW QNKSVKRSNR 300
YSYLSPLQIQ QIPIPKLAAP NCLLVTWVTN RQKHLRFIKE ELYPSWSVEV VAEWHWVKIT 360
NSGEFVFPLD SPHKKPYEGL ILGRVQEKTA LPLRGFKRLH QARWGIFGVV CSKFTARLD 419 
Gene Ontology
 GO:0008168; F:methyltransferase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro. 
Interpro
 IPR002052; DNA_methylase_N6_adenine_CS.
 IPR007757; MT-A70-like. 
Pfam
 PF05063; MT-A70 
SMART
  
PROSITE
 PS51143; MT_A70
 PS00092; N6_MTASE 
PRINTS