CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031472
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nuclear receptor coactivator 3 
Protein Synonyms/Alias
 cDNA FLJ53588, highly similar to Translocation-associated membrane protein 1 
Gene Name
 TRAM1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
252LARAENQKLDFSTGNubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 343 AA 
Protein Sequence
MVFLLGLMFE ITAKASIIFV TLQYNVTLPA TEEQATESVS LYYYGIKDLA TVFFYMLVAI 60
IIHAVIQEYM LDKINRRMHF SKTKHSKFNE SGQLSAFYLF ACVWGTFILI SENYISDPTI 120
LWRAYPHNLM TFQMKFFYIS QLAYWLHAFP ELYFQKTKKE DIPRQLVYIG LYLFHIAGAY 180
LLNLNHLGLV LLVLHYFVEF LFHISRLFYF SNEKYQKGFS LWAVLFVLGR LLTLILSVLT 240
VGFGLARAEN QKLDFSTGNF NVLAVRIAVL ASICVTQAFM MWKFINFQLR RWREHSAFQA 300
PAVKKKPTVT KGRSSKKGTE NGVNGTLTSN VADSPRNKKE KSS 343 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR006634; TLC-dom.
 IPR013599; TRAM1.
 IPR016447; Translocation_assoc_membrane. 
Pfam
 PF08390; TRAM1
 PF03798; TRAM_LAG1_CLN8 
SMART
 SM00724; TLC 
PROSITE
 PS50922; TLC 
PRINTS