CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006836
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable transcriptional regulator NRG2 
Protein Synonyms/Alias
  
Gene Name
 NRG2 
Gene Synonyms/Alias
 YBR066C; YBR0616 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
156QRTRHFCKICSTGFTubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Transcriptional repressor (By similarity). 
Sequence Annotation
 ZN_FING 153 175 C2H2-type 1.
 ZN_FING 181 205 C2H2-type 2.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 220 AA 
Protein Sequence
MSIGYKDNLM STILAKDRKC EFPINFECSP SQITLMPEMF SFNNERKYQT LIPLMKTSHL 60
IDDDLKDKLN KCAFDFFSGK QANRTSDGTI SRLTASGKTS PILPLQNINI VKAENTGNGK 120
SDPYSSIKIS KPTKTVIKLK STKTNTAGQR TRHFCKICST GFTTSGHLSR HNRIHTGEKN 180
HICPHEGCGQ RFSRHDNCNQ HYRTHANKKK RNWKRREASS 220 
Gene Ontology
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0043565; F:sequence-specific DNA binding; IDA:SGD.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0042710; P:biofilm formation; IGI:SGD.
 GO:1900464; P:negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from RNA polymerase II promoter; IGI:SGD.
 GO:1900460; P:negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter; IGI:SGD.
 GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.
 GO:0007124; P:pseudohyphal growth; IGI:SGD.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
  
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS