UniProt Accession

 HXB7_HUMAN; P09629; A8K3N8; Q15957; Q53FN3; Q96BQ6 

Genbank Protein ID

 M16937; AK290653; AK223249; AC103702; CH471109; BC015345; S49765; M30598 

Genbank Nucleotide ID

 AAA36003.1; BAF83342.1; BAD96969.1; EAW94725.1; AAH15345.1; AAB19469.2; AAA36005.1 

Protein Name

 Homeobox protein Hox-B7 

Protein Synonyms/Alias

 Homeobox protein HHO.C1; Homeobox protein Hox-2C 

Gene Name

 HOXB7 

Gene Synonyms/Alias

 HOX2C 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
191	WFQNRRMKWKKENKT	ubiquitination	[1]
193	QNRRMKWKKENKTAG	ubiquitination	[1]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. 

Sequence Annotation

 DNA_BIND 137 196 Homeobox.
 MOTIF 126 131 Antp-type hexapeptide.
 CROSSLNK 191 191 Glycyl lysine isopeptide (Lys-Gly)
 CROSSLNK 193 193 Glycyl lysine isopeptide (Lys-Gly)  

Keyword

 Complete proteome; Developmental protein; DNA-binding; Homeobox; Isopeptide bond; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 217 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; NAS:UniProtKB.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
 GO:0009952; P:anterior/posterior pattern specification; IEA:Compara.
 GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Compara.
 GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
 GO:0030099; P:myeloid cell differentiation; IEA:Compara.
 GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IEA:Compara.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR017995; Homeobox_antennapedia.
 IPR001827; Homeobox_Antennapedia_CS.
 IPR017970; Homeobox_CS.
 IPR020479; Homeobox_metazoa.
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like. 

Pfam

 PF00046; Homeobox 

SMART

 SM00389; HOX 

PROSITE

 PS00032; ANTENNAPEDIA
 PS00027; HOMEOBOX_1
 PS50071; HOMEOBOX_2 

PRINTS

 PR00025; ANTENNAPEDIA.
 PR00024; HOMEOBOX.