| Tag | Content |
|---|
| CPLM ID | CPLM-016474 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | RUN and FYVE domain-containing protein 1 |
Protein Synonyms/Alias | Rab4-interacting protein |
Gene Name | Rufy1 |
Gene Synonyms/Alias | Rabip4 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 359 | DRICSLQKEQQQLRE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. |
Sequence Annotation | DOMAIN 143 275 RUN.
ZN_FING 646 704 FYVE-type.
REGION 619 629 Interaction with RAB4.
MOD_RES 393 393 Phosphotyrosine (By similarity).
MOD_RES 404 404 Phosphotyrosine (By similarity). |
Keyword | Coiled coil; Complete proteome; Cytoplasm; Endocytosis; Endosome; Lipid-binding; Membrane; Metal-binding; Phosphoprotein; Protein transport; Reference proteome; Transport; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 712 AA |
Protein Sequence | MAARGECRRA GQDSEPEPER EPESEPGPEP EPQAGLESGE AFEIVDRSQL PSPGELRSAS 60
RPRVADSWSA PILTLARRAT GNLSASCGSA LRAAAGLGDG GGGGERAASK GQMMEERANL 120
MHMMKLSIKV LLQSALSLGR SLDADYAPLQ QFFVVMEHCL KHGLKVKKSF IGQNKSFFGP 180
LELVEKLCPE ASDIATSVRN LPELKTAVGR GRAWLYLALM QKKLADYLKV LIDNKQLLSE 240
FYEPEALMME EEGMVIVGLL VGLNVLDANL CLKGEDLDSQ VGVIDFSLCL KDAQDLDSGR 300
EHERITDVLD QKNYVEELNR HLSCTVGDLQ TKIDGLEKTN SKLQEELSAA TDRICSLQKE 360
QQQLREQNEV IRERSEKSVE ITKQDTKVEL ETYKQTRQGL DEMYSDVWKQ LKEEKKVRLE 420
LEKELELQIG MKTEMEIAMK LLEKDTHEKQ DTLVALRQQL EEVKAINLQM FHKVQSAESS 480
LQQKNEAIAS FEGKTTQVMS SMKQMEERLQ QAERARQAAE ERSHKLQQEL SGRGSALQLQ 540
LSQLRDQCSG LEKELKSEKE QRQALQRELQ REKDTSCLLQ TELQQVEGLK KELRELQDEK 600
AELRKVCEEQ EQALQEMGLH LSQSKLKMED IKEVNKALKG HTWLKDDEAT HCKQCEKDFS 660
ISRRKHHCRN CGHIFCNTCS SNELALPSYP KPVRVCDSCH TLLLQRCSST AS 712 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |