UniProt Accession

 SSRB_HUMAN; P43308; B2R9K9; D3DVA7; Q53HI0; Q5VY95; Q5VY96; Q6IB31; Q9BWE4 

Genbank Protein ID

 X74104; D37991; AY251536; CR456973; AK222600; AK313821; AL355388; AL355388; CH471121; CH471121; BC000341 

Genbank Nucleotide ID

 CAA52207.1; BAA07206.1; AAP20059.1; CAG33254.1; BAD96320.1; BAG36556.1; CAH72631.1; CAH72632.1; EAW53010.1; EAW53011.1; AAH00341.2 

Protein Name

 Translocon-associated protein subunit beta 

Protein Synonyms/Alias

 TRAP-beta; Signal sequence receptor subunit beta; SSR-beta 

Gene Name

 SSR2 

Gene Synonyms/Alias

 TRAPB; HSD25 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
27	GARLLASKSLLNRYA	ubiquitination	[1, 2, 3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
 Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR.
 J Biol Chem. 2011 Dec 2;286(48):41530-8. [PMID: 21987572]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. 

Sequence Annotation

 CARBOHYD 88 88 N-linked (GlcNAc...).
 CARBOHYD 104 104 N-linked (GlcNAc...).  

Keyword

 Complete proteome; Endoplasmic reticulum; Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 183 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; TAS:ProtInc.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; TAS:ProtInc.
 GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
 GO:0006412; P:translation; TAS:Reactome. 

Interpro

 IPR008856; TRAP_beta. 

Pfam

 PF05753; TRAP_beta 

SMART

  

PROSITE

  

PRINTS