CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035477
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Bcor 
Protein Synonyms/Alias
  
Gene Name
 Bcor 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
30CGTSEDRKIPVNDGDubiquitination[1]
40VNDGDASKARLELREubiquitination[1]
374SPSVTLTKPYMTASSacetylation[2]
392TARLSSGKYPKALDGacetylation[2]
1462ARRLIVNKNAGETLLubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1757 AA 
Protein Sequence
MLSATPLYGN VHSWMNSERV RMCGTSEDRK IPVNDGDASK ARLELREENP LNHNVVDTSG 60
AHRIDGLAAL SMDRTGLIRE GLRVPGNIVY SGLCGLGSEK GREATPSSLS GLGFSSERNP 120
EMQFKPNTPE TVEASAVSGK PPNGFSAIYK TPPGIQKSAV ATAESLGLDR PASDKQSPLN 180
INGASYLRLP WVNPYMEGAT PAIYPFLDSP NKYSLNMYKA LLPQQSYGLA QPLYSPVCTS 240
GERFLYLPPP HYVNPHIPSS LASPMRLSTP SASAAIPPLV HCSDKSLPWK MGVNPGNPVD 300
SHTYPHIQNS KQPRVTSAKA VNSGLPGDAA LLLPPSPRPS TRVHLPTQPA AESYSEFHKH 360
YPRISTSPSV TLTKPYMTAS SEFPTARLSS GKYPKALDGG DCAPSMSGHS RKTTVQDRKD 420
GGSPPLLEKQ TVTKDVTDKP LDLSSKVVDV DTSKTDHMKK MAPTVLVHSR ATSGLVLSGS 480
EIPKETSPPG NGCSIYRSEI ISTAPSSWVV PGPSPNEENN GKSLSLKNKA LDWAIPQQRS 540
SSCPRMGGTD AVITNVSGSV SSSGRPASAS PAPNANADGT KTSRSSVDTT PSVIQHVGQP 600
PSTPAKHSGS TSSKGAKASN PEPSFKASEN GLPPTSIFLS PNEAFRSPPI PYPRSYLPYP 660
APEGIALSPL SLHGKGPVYP HPVLLPNGSL FPGHLAPKPG LPYGLHTSRP EFVTYQDALG 720
LGMVHPMLIP HTPIEITKEE KPERRSRSHE RARYEDPTLR SRFSEILEAS SAKLHPDVPT 780
EKNLKPNPSW NQGKTGAKSD KLVYVDLLRE ETEAKADAGA SKAGLVAENA GQNTDAAKPS 840
ADPVIQQHRE FISLREELGR ITDFHESFTF KQAPGQPVFS LGKDSVAAGS NKENLGVQVA 900
TPFLETALGS EGPAVTFGKT QEDPKPFCVG GAPPSMDVTP AYTKDGTDEA ESNDGKVLKP 960
KPSKLAKRIA NSAGYVGDRF KCVTTELYAD SSQLSREQRA LQMEGLQEDS ILCLPAAYCE 1020
RAMMRFSELE MKEREVSHPA TKDSEVCKFS PADWERLKGN QEKKPKSVAL EEAIADQNDT 1080
ERCDCSTGNK HDLFEAPEDK DLPVEKYFLE RPPVSEPPTD QGVVDMSHSP TLRLDRKRKA 1140
SGDSTHTETT VEELTEDPLK AKRRRISKDD WPEREMTNSS SNHLEDPHCN ELTNLKVCIE 1200
LTGLHPKKQR HLLHLRERWE QQVSAAESKP GRQSRKEVTQ AVQPEVTSQG NNITEERPGR 1260
KKAEAKGNRG WSEESLKSCD NEQGLPVFSA SPPMKSLSST NASGKKQTQP SCTPASRPPA 1320
KQQKIKESQK TDVLCTEEDE DCRAASPLQK YTDNIEKPSG KRLCKTKHLI PQDSRRSVQI 1380
TGEYYVENTD TKMTVRRFRK RPEPSTDYDL SPPAKQEPKP FDRLQQLLPA TQATQLPRSN 1440
SPQETTQSRP MPPEARRLIV NKNAGETLLQ RAARLGYEEV VLYCLENKVC DVNHRDNAGY 1500
CALHEACARG WLNIVRHLLE YGADVNCSAQ DGTRPLHDAV ENDHLEIVRL LLSYGADPTL 1560
ATYSGRTIMK MTHSELMEKF LTDYLNDLQG RSEEDTSGAW EFYGSSVCEP DDESGYDVLA 1620
NPPGPEDPDE EEDAYSDMFE FEFAESSLLP CYNIQVSVAQ GPRNWLLLSD VLKKLKMSSR 1680
IFRCNFPNME IVSIAEAEFY RQVSTSLLFS CPKDLEAFNP EGKELLDLVE FTNELQTLLG 1740
SSVEWLHPSD TGHENYW 1757 
Gene Ontology
 GO:0031519; C:PcG protein complex; IEA:Compara.
 GO:0003714; F:transcription corepressor activity; IEA:Compara.
 GO:0044212; F:transcription regulatory region DNA binding; IEA:Compara.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:Compara.
 GO:0007507; P:heart development; IEA:Compara.
 GO:0035518; P:histone H2A monoubiquitination; IEA:Compara.
 GO:0030502; P:negative regulation of bone mineralization; IEA:Compara.
 GO:0000415; P:negative regulation of histone H3-K36 methylation; IEA:Compara.
 GO:0051572; P:negative regulation of histone H3-K4 methylation; IEA:Compara.
 GO:0070171; P:negative regulation of tooth mineralization; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0042476; P:odontogenesis; IEA:Compara.
 GO:0060021; P:palate development; IEA:Compara.
 GO:0065001; P:specification of axis polarity; IEA:Compara. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom. 
Pfam
 PF12796; Ank_2 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS