CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041060
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Exonuclease 3'-5' domain-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 Exd2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
419GIGELVSKEPFVVRLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 650 AA 
Protein Sequence
MSRQNLVALT VTTLLGVAMG GFVLWKGIQR RWSKTSRVMQ QQPQQPQQPQ QPQPQPQPQP 60
QPQPEHPQPQ QQVPGGREWP PPEDDQLPFG ALRAPRASWE ERILQAEVVT VSQEAEWNQI 120
QPFLKRELED FPVLGIDCEW VNLEGKASPL SLLQMASPSG FCALVRLPRL IYGGRTLPRT 180
LLDILADGAI LKVGVGCSED ANKLLQDYGL IVRGCLDLRY LAMKQGNNIL CNGLSLKSLA 240
ETILNFPLDK SLLLRCSNWD AENLTEDQVT YAARDAQISV ALFLHLLGYP FSRDSYEEES 300
TDQINWQKAL ERCRNMVDIP FRSKGLGRLV EEVNGEALES QLKPRNRKAK TDRMVPGNNQ 360
GRDPRKHKRK PLGVGYSARK SPLYDNCFLQ APDGQPLCTC DRRKAQWYLD KGIGELVSKE 420
PFVVRLQFEP AGRPESPGDY YLMVKENLCV VCGKTDTYIR KNIIPHEYRK HFPIEMKDHN 480
SHDVLLLCTS CHAISNYYDN HLKQQLAKEF QAPIGSEEGL RLLEDLERRQ VRSGARALLN 540
AESLPAHRKE ELLHALREFY NTDIITEEML HEAASLETRI YNESYIPHGL KVVQRHTEGG 600
LRSLMQLESR WRQHFLDSMQ PKHLPQQWSV DHNHQKLLRK YGDDLPIKLS 650 
Gene Ontology
 GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR002562; 3'-5'_exonuclease_dom.
 IPR012337; RNaseH-like_dom. 
Pfam
 PF01612; DNA_pol_A_exo1 
SMART
 SM00474; 35EXOc 
PROSITE
  
PRINTS