| Tag | Content |
|---|
| CPLM ID | CPLM-013963 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Probable ATP-dependent RNA helicase DDX59 |
Protein Synonyms/Alias | DEAD box protein 59; Zinc finger HIT domain-containing protein 5 |
Gene Name | DDX59 |
Gene Synonyms/Alias | ZNHIT5 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 253 | SADTGSGKTAAFLLP | ubiquitination | [1] | | 270 | MRALFESKTPSALIL | ubiquitination | [1] | | 410 | VRIITGEKNLPCANV | ubiquitination | [1] | | 440 | LFEILNDKKLFKPPV | ubiquitination | [1] | | 471 | VQKITGLKSISIHSE | ubiquitination | [1] | | 562 | RLFWDIAKRVKPTGS | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | DOMAIN 234 405 Helicase ATP-binding.
DOMAIN 416 579 Helicase C-terminal.
ZN_FING 104 133 HIT-type.
NP_BIND 247 254 ATP (By similarity).
MOTIF 203 231 Q motif.
MOTIF 353 356 DEAD box.
MOD_RES 64 64 Phosphoserine.
MOD_RES 160 160 Phosphoserine. |
Keyword | 3D-structure; Alternative splicing; ATP-binding; Complete proteome; Helicase; Hydrolase; Metal-binding; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; RNA-binding; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 619 AA |
Protein Sequence | MFVPRSLKIK RNANDDGKSC VAKIIKPDPE DLQLDKSRDV PVDAVATEAA TIDRHISESC 60
PFPSPGGQLA EVHSVSPEQG AKDSHPSEEP VKSFSKTQRW AEPGEPICVV CGRYGEYICD 120
KTDEDVCSLE CKAKHLLQVK EKEEKSKLSN PQKADSEPES PLNASYVYKE HPFILNLQED 180
QIENLKQQLG ILVQGQEVTR PIIDFEHCSL PEVLNHNLKK SGYEVPTPIQ MQMIPVGLLG 240
RDILASADTG SGKTAAFLLP VIMRALFESK TPSALILTPT RELAIQIERQ AKELMSGLPR 300
MKTVLLVGGL PLPPQLYRLQ QHVKVIIATP GRLLDIIKQS SVELCGVKIV VVDEADTMLK 360
MGFQQQVLDI LENIPNDCQT ILVSATIPTS IEQLASQLLH NPVRIITGEK NLPCANVRQI 420
ILWVEDPAKK KKLFEILNDK KLFKPPVLVF VDCKLGADLL SEAVQKITGL KSISIHSEKS 480
QIERKNILKG LLEGDYEVVV STGVLGRGLD LISVRLVVNF DMPSSMDEYV HQIGRVGRLG 540
QNGTAITFIN NNSKRLFWDI AKRVKPTGSI LPPQLLNSPY LHDQKRKEQQ KDKQTQNDLV 600
TGANLMDIIR KHDKSNSQK 619 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |