CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027446
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcriptional activator ADA2, putative 
Protein Synonyms/Alias
  
Gene Name
 PF10_0143 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
1032SSYSIAQKLPRHVMDacetylation[1]
1082QFNSVSLKFPYKGSSacetylation[1]
1682NDDYVLPKSKKNNRTacetylation[1]
1684DYVLPKSKKNNRTQIacetylation[1]
1685YVLPKSKKNNRTQIIacetylation[1]
1871VTTEKLGKSLKTSKKacetylation[1]
1874EKLGKSLKTSKKDYKacetylation[1]
1877GKSLKTSKKDYKIKNacetylation[1]
1878KSLKTSKKDYKIKNKacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2578 AA 
Protein Sequence
MNINKYEEFY PSILMHERQC GLSSAYIVYE KEQLEILEQE VLKAIIIKAL IIEEVIKYIK 60
CILYKIELIK YNNNNNNNNN NNNDNIILTS YDNTNIRKNQ IKNVYCPKLL NKNNNIIYDN 120
NLIKDIDRNN FKNKLYIIQF NGNESVRRNF FKTEQKNTIS NDNIRIQGND VIENKNEKIN 180
KSLCNIISNE NKEIVLNKKN LDTLMLLEKI KTKTISFINK SSYVVIYKSI NDYNNVLQKE 240
LIDISSKCCN NKFQLYSKNI NSYSIIDYVT GHINKMKEYQ MRNKFLDDII VKIKDELYIN 300
IDLIYKNKNN KSFLSVMENI NYTIVNTYNI NQDKLESFKY LHFNFFYICS KLENKSISNI 360
NKYNKVNNNI CNIFLYFFVM IFFHLYIQNS DDKRKEDICN NFYNILKYNS YNYEKFYVFI 420
LLCIKCIVSI RNDKLINFVP HNGRKKFSND DNKELYNDNS TEKKMTIRTG YHFKFNINKK 480
SIHNRNYYFI NYAHHVIFNT LYYCIVKGCN IYYKIKKSKE FKRNTYYNNN NYQWTNYFNY 540
IQLYNKCKKI NNKYRKMKII GEIILSKNLK YENNKKNKTG SDRLSGTYFL YNNNKKRNYF 600
IVYYKRYIKR GYANSGNNKQ KMFCFKNDNI VLLNKIILYL IDKNRKDAIK KDKLNIKEWH 660
RNTKLYCNSN NAEGGDGGYN NHSNSNYRNN GNNNIGNYNN NGSNFFGNNM GGNNNDNDDN 720
DNNDENNYKP KNTCNDDDND NDNDGGNKNN SGKYNNSVNK NDNNNNNNST DGVYGNNVDN 780
VNNVMMNHYG DKIPISNENG YDNNSNVIHK KMVDNKLEGI NKSASNNNMI NNKVMNSAGM 840
MSSNGDMNYN LNYMNYMNNT NNINMPGSGG GSGVNRMTTV PINHVMNFPN SYMSGANMPS 900
QVPQNMHFDA IENMHDMKQT PQQMKHKTSQ LNSSANQGDI NNNAKQVGGL PANFMQNQMH 960
PQYQYQQQVH MQQLVQQQNV HGYNNMMQSN NQQKFPNQPG AHKQSNASIL KMPPFSSLNS 1020
GDQRSSYSIA QKLPRHVMDT NNNVPSINNN NSSSNNNNNP RHSSSNMPSL NNPNQFNSVS 1080
LKFPYKGSSP QPLNSINNNN NPNQPNQQNH QNQPNHMPNI SAQQNMQNVN NNNNNPSVVQ 1140
QMNVNHPIMQ HNMIQQNQNN MHNLAPNKPN ESQSMFPLGA SSNQQGNMQN IASPNKQKMQ 1200
PLFQQGGQQI IAPNQKGINT ASISGSISRQ PNQGTGQIPI SHQNIQQFYH NNSGQMFPQQ 1260
PPFLQRVSTT PQHVPQQQVP YEWMNNPYMH HQYMLQQCQL TPQQLFMHQQ KQQNNMLHHQ 1320
QQQQQQLQHQ QMQQQQLHQQ QIQQQQLHQQ QIQQQQLHQQ QIQQQQIQQQ QLQQQQLQQQ 1380
QIQQHQLQQQ QQQQQQGNIP PLSARQSKQG ILQMQSQNNI SHLPPNLEQH FQQQNISELQ 1440
HHQQQMQNVS AQHSSISTFE PNAQQTMYQG EMFKDSNILQ GGHNLEIVDG VNEMQRTNDA 1500
FKGGNIIEAS NVSLEAITEE DIFDSNYHCD ICNKDITHTI RIRCAECVDF DLCVNCFSTG 1560
KEMKSDKCEH YNYHNYIPIP KYDFPLYKLN WSAEEELLLL DGISKFGFGN WEQVADLVNS 1620
VANITKTDRE CESHYYNFYL KSNCAPLPDN KRLLIKPDGN PYEIEHVVEK DINDNDDYVL 1680
PKSKKNNRTQ IIGYWPLRGD FDIEYDNDAE LLLADMEFKE SDLPQQKELK LQVLEIYNSK 1740
LDERIYRKRT VIERGLLDSK AQMQKEKKRT KEEKELYAAL KPLSRFHSPQ HHEYFIQLLL 1800
EEQKLRQRLT KLQEWKALGL QNIEQVQEYE IEKNRRAKEM VKQESNSTTG IISMNNISSN 1860
NNTVTTEKLG KSLKTSKKDY KIKNKEEETD ENKKLNIDTF VALDLLNEKE VEFCKNMKLP 1920
ILFFLLIKRL LIMEVSNSNL NMLKDINELK LKGYKVGQLY DFFLSFDINQ KDEFLNNGTV 1980
NTSYVKKNDG KRKKSKNNFD ISNSKEIDGK EKLVVDDKDE KNDKNSSNNN NNNNNNNNNN 2040
NNNNNANVDN YNVYVDNNNS GNYSLMTLQG EVLNENEKKG KSKNEDKNKT SNLATKNSNK 2100
GCNKLKSPPK DDMNDINKDA KDIIIKNTND MILTECVNDK NMQSIFVDNN LESENNDQLK 2160
ENEVKGDELN LTEKELNEHI LNTVVVDEND KKGKNEKGKN CETQKNMDSN LLQNEVDMKS 2220
NESLFNEKKK GSIKRKSSII NNLYDKVHEN NENVDILENE VKDNVTVDDI KENKEIPNGI 2280
TETFESIENI EEEKDMTMKD IKNDNKDDTK NDCDNEKDDD DYVAQEEILE DDKKRRKKKK 2340
EKKSEYADDK NDELNSIKIN ENECTSNDIE EDIKSIKSLR KKSYEKIKGF TAHLKTNSNN 2400
KKKTNDNFDE IEKETTVSVN INDSNNRKAK KKTPEKVETN NYQAHVEPLE NNSKKKNTKM 2460
RKTSEYSVTR NESKINNNSD VYNDNSITKD DSNIDLDDKP SKSKKSISST STVILNKNEK 2520
GKRTKLTKEK ATVDIPSNVD TKENDKKMKN FEANLKKKAK KRKGSVSLIL NPKKSLKL 2578 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0003682; F:chromatin binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:GeneDB_Pfalciparum.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR009057; Homeodomain-like.
 IPR001005; SANT/Myb.
 IPR017884; SANT_dom.
 IPR000433; Znf_ZZ. 
Pfam
 PF00249; Myb_DNA-binding
 PF00569; ZZ 
SMART
 SM00717; SANT
 SM00291; ZnF_ZZ 
PROSITE
 PS51293; SANT
 PS01357; ZF_ZZ_1
 PS50135; ZF_ZZ_2 
PRINTS