CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025995
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable thiol peroxidase 
Protein Synonyms/Alias
  
Gene Name
 tpx 
Gene Synonyms/Alias
 GK2787 
Created Date
 July 27, 2013 
Organism
 Geobacillus kaustophilus (strain HTA426) 
NCBI Taxa ID
 235909 
Lysine Modification
Position
Peptide
Type
References
7*MAYVTFKGQPVTLVacetylation[1]
19TLVGNEVKVGDKAPDacetylation[1]
122QAYGVLIKELRLLARacetylation[1]
Reference
 [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus.
 Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG.
 Proteomics. 2013 Aug;13(15):2278-82. [PMID: 23696451] 
Functional Description
 Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity). 
Sequence Annotation
 DOMAIN 18 166 Thioredoxin (By similarity).  
Keyword
 Antioxidant; Complete proteome; Oxidoreductase; Peroxidase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 166 AA 
Protein Sequence
MAYVTFKGQP VTLVGNEVKV GDKAPDFTVL DQNLQEVTLA DTKGHVRLIS VVPSLDTGVC 60
DAQTRRFNEE AAKLDNVKVL TISVDLPFAQ KRWCGAAGIE NVQVLSDHRD VSFGQAYGVL 120
IKELRLLARA VFVIDSNDTV TYVEYVPEVT NHPNYEAAIE AAKAAK 166 
Gene Ontology
 GO:0008379; F:thioredoxin peroxidase activity; IEA:HAMAP.
 GO:0045454; P:cell redox homeostasis; IEA:HAMAP. 
Interpro
 IPR018219; Antioxidant_Tpx_CS.
 IPR002065; Put_TPX.
 IPR013740; Redoxin.
 IPR012336; Thioredoxin-like_fold. 
Pfam
 PF08534; Redoxin 
SMART
  
PROSITE
 PS51352; THIOREDOXIN_2
 PS01265; TPX 
PRINTS