CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023450
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable cytochrome P450 4d20 
Protein Synonyms/Alias
 CYPIVD20 
Gene Name
 Cyp4d20 
Gene Synonyms/Alias
 CG16761 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
392AIGRHAQKELEIGDKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides (By similarity). 
Sequence Annotation
 METAL 455 455 Iron (heme axial ligand) (By similarity).  
Keyword
 Complete proteome; Endoplasmic reticulum; Heme; Iron; Membrane; Metal-binding; Microsome; Monooxygenase; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 510 AA 
Protein Sequence
MWLTLITGAL ILLLTWDFGR KRQRVLAFEK SAIPGPISIP ILGCGLQALH LGAENIIGWV 60
GEKFDKYGKT FRFWILGESL IYTKDLQYFE TILSSTTLLE KGQLYEYLRP FLNDGLLVST 120
GRKWHARRKI FTHAFHFKVL EHYVEIMDRH SSVMVDNLRK VADGKTAVDM LKYVSLAALD 180
VITEAAMGVQ VNAQNDPDFP YIKALKSVVY IQPDRMFRFS RRYNWLFPLA APLLHRQLLS 240
DIRVMHDFTD KVISERRETV RRAKADGTYR PLSLGDAEIG SKSQMALLDI LLQSSINNQP 300
LSDADIREEV DTFMFEGDDT TSSGVSHALY AIARHPEVQQ RIFEELQRVL GPDASAPVTQ 360
AQLQDLKYLD CVIKETMRLY PPVPAIGRHA QKELEIGDKT IPANTSIYLV LYYAHRDANY 420
FPDPLSFRPE RFLEDQEQGH NTFAYVPFSA GPKNCIGQKF AVLEMKVLIS KVLRFYELLP 480
LGEELKPMLN FILRSASGIN VGLRPRKALR 510 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
 GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. 
Interpro
 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR002401; Cyt_P450_E_grp-I. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
 PS00086; CYTOCHROME_P450 
PRINTS
 PR00463; EP450I.
 PR00385; P450.