CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025007
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NR1 protein 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Schistosoma mansoni (Blood fluke) 
NCBI Taxa ID
 6183 
Lysine Modification
Position
Peptide
Type
References
197NCDSERCKKQLLNNSacetylation[1]
198CDSERCKKQLLNNSIacetylation[1]
344VRKRRQGKKREQSSCacetylation[1]
345RKRRQGKKREQSSCEacetylation[1]
Reference
 [1] Cloning of SmNCoA-62, a novel nuclear receptor co-activator from Schistosoma mansoni: assembly of a complex with a SmRXR1/SmNR1 heterodimer, SmGCN5 and SmCBP1.
 Fantappié MR, Bastos de Oliveira FM, de Moraes Maciel R, Rumjanek FD, Wu W, Loverde PT.
 Int J Parasitol. 2008 Aug;38(10):1133-47. [PMID: 18359485] 
Functional Description
  
Sequence Annotation
  
Keyword
 DNA-binding; Metal-binding; Nucleus; Receptor; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 715 AA 
Protein Sequence
MSHCPVEYSN PNSQNTISYI TSDSVISVSF ADCQSSSPSY HSLSSSTALP GVGSFLDKSN 60
HLPHYSPNKY YDTEPTAIPG HSYVENTDVF DNNLPYPIKS EAIHETVSGT FITPDAHNES 120
CFTSPLQPLK SLNPSLPVQS SESLLSGFTH PLSMDHTVLE DGGLDLDRVF VAIINDRNSE 180
HDIFNDNDVN CDSERCKKQL LNNSIQSSVN QSMLTDDSED KSLLQYYSVI DSEKTTQHQT 240
HPKTSPISEV EQTHKSSGSS EVSTRMCVVC GDKASGFHYG VSTCEGCKGF FRRAIQRDQS 300
YTCAKNGTCE INKTLRNKCQ QCRLLKCIAV GMSRDAVRKR RQGKKREQSS CESVTLPSSD 360
SSNKYEGSAY SSCSADVVLT PSKAHLNETT PDPHEMPIKS INFQPSSSIP SSTNISLTLC 420
NNNNNNSNNS NNLTKEDQQT LDKFDRFLNY CKDQAIKYQA NNWNISKSDY YHLSGSLSRH 480
LSPIKHTPHE LGESLKLLTV DEIFCPAQLK FTHEFACHLE QFIRLSQHDQ AILLRDCLPE 540
LAILMLCREN RNKTHMNSSS TSINYQLNCL FSPWFSNAVV TDSSLDCLHM TCDSITAQSI 600
FQFASRLQRL HLTNMEFGPL IGVILFTPER SDLLDIDFVN RTQNLWAELL RRYCESNGSQ 660
TRCAHLIMIL STLRELASKI THNLNAWYKL SNTPMSNCLK EFLYSSSFNS MDDCF 715 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR008946; Nucl_hormone_rcpt_ligand-bd.
 IPR000536; Nucl_hrmn_rcpt_lig-bd_core.
 IPR001723; Str_hrmn_rcpt.
 IPR001628; Znf_hrmn_rcpt.
 IPR013088; Znf_NHR/GATA. 
Pfam
 PF00104; Hormone_recep
 PF00105; zf-C4 
SMART
 SM00430; HOLI
 SM00399; ZnF_C4 
PROSITE
 PS00031; NUCLEAR_REC_DBD_1
 PS51030; NUCLEAR_REC_DBD_2 
PRINTS
 PR00398; STRDHORMONER.
 PR00047; STROIDFINGER.