CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035674
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dynactin 1, isoform CRA_a 
Protein Synonyms/Alias
 Dynactin subunit 1 
Gene Name
 Dctn1 
Gene Synonyms/Alias
 rCG_56074 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
230QVRDLEEKLETLRLKacetylation[1]
284KEARKEAKEALEAKEacetylation[1]
290AKEALEAKERYMEEMacetylation[1]
962LKKSLKIKGEELSEAacetylation[1]
1154LSGALYRKTSQLLEKubiquitination[2]
1161KTSQLLEKLNQLSTHacetylation[1]
1204SLSDTIEKLKDEVLKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1281 AA 
Protein Sequence
MAQSKRHMYN RTPSGSRMST EASARPLRVG SRVEVIGKGH RGTVAYVGAT LFATGKWVGV 60
ILDEAKGKND GTVQGRKYFT CDEGHGIFVR QSQIQVFEDG ADTTSPETPD SSASKILKRE 120
GADAAAKTSK LRGLKPKKAP TARKTTTRRP KPTRPASTGV AGPSSSLGPS GSASAGELSS 180
SEPSTPAQTP LAAPIIPTPA LTSPGAAPPL PSPSKEEEGL RAQVRDLEEK LETLRLKRSE 240
DKAKLKELEK HKIQLEQVQE WKSKMQEQQA DLQRRLKEAR KEAKEALEAK ERYMEEMADT 300
ADAIEMATLD KEMAEERAES LQQEVEALKE RVDELTTDLE ILKAEIEEKG SDGAASSYQL 360
KQLEEQNARL KDALVRMRDL SSSEKQEHVK LQKLMEKKNQ ELEVVRQQRE RLQEELSQAE 420
STIDELKEQV DAALGAEEMV EMLTDRNLNL EEKVRELRET VGDLEAMNEM NDELQENARE 480
TELELREQLD MAGARVREAQ KRVEAAQETV ADYQQTIKKY RQLTAHLQDV NRELTNQQEA 540
SVERQQQPPP ETFDFKIKFA ETKAHAKAIE MELRQMEVAQ ANRHMSLLTA FMPDSFLRPG 600
GDHDCVLVLL LMPRLICKAE LIRKQAQEKF DLSENCSERP GLRGAAGEQL SFAAGLVYSL 660
SLLQATLHRY EHALSQCSVD VYKKVGSLYP EMSAHERSLD FLIELLHKDQ LDETVNVEPL 720
TKAIKYYQHL YSIHLAEQPE ESTMQLADHI KFTQSALDCM SVEVGRLRAF LQGGQEATDI 780
ALLLRDLETS CSDIRQFCKK IRRRMPGTDA PGIPAALAFG SQVSDTLLDC RKHLTWVVAV 840
LQEVAAAAAQ LIAPLAENEG LPVAALEELA FKASEQIYGS PSSSPYECLR QSCSILISTM 900
NKLATAMQEG EYDAERPPSK PPPVELRAAA LRAEITDAEG LGLKLEDRET VIKELKKSLK 960
IKGEELSEAN VRLSLLEKKL DSAAKDADER IEKVQTRLEE TQTLLRKKEK EFEETMDALQ 1020
ADIDQLEAEK TELKQRLNSQ SKRTIEGLRG PPPSGIATLV SGIAGEEQQR GGTPGQAPGA 1080
LPGPGPVKDS PLLLQQISAM RLHISQLQHE NSILRGAQMK ASLAALPPLH VAKFSLPPHE 1140
GPGGNLLSGA LYRKTSQLLE KLNQLSTHTH VVDITRSSPA AKSPSAQLME QVAQLKSLSD 1200
TIEKLKDEVL KETVTQRPGA TVPTDFATFP SSAFLRAKEE QQDDTVYMGK VTFSCAAGLG 1260
QRHRLVLTQE QLHQLHGRLI S 1281 
Gene Ontology
 GO:0031252; C:cell leading edge; IEA:Compara.
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0000776; C:kinetochore; IEA:Compara.
 GO:0005874; C:microtubule; IEA:Compara.
 GO:0000922; C:spindle pole; IEA:Compara. 
Interpro
 IPR000938; CAP-Gly_domain.
 IPR022157; Dynactin. 
Pfam
 PF01302; CAP_GLY
 PF12455; Dynactin 
SMART
 SM01052; CAP_GLY 
PROSITE
 PS00845; CAP_GLY_1
 PS50245; CAP_GLY_2 
PRINTS