UniProt Accession

 B4DW75_HUMAN; B4DW75 

Genbank Protein ID

 AC010895; AC096549; AK301402 

Genbank Nucleotide ID

 BAG62937.1 

Protein Name

 EGF-containing fibulin-like extracellular matrix protein 1 

Protein Synonyms/Alias

 cDNA FLJ53670, highly similar to EGF-containing fibulin-like extracellularmatrix protein 1 

Gene Name

 EFEMP1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
149	QCPPGYQKRGEQCVD	ubiquitination	[1, 2]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Disulfide bond; EGF-like domain; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 355 AA 

Protein Sequence

Gene Ontology

 GO:0005509; F:calcium ion binding; IEA:InterPro. 

Interpro

 IPR026824; Efemp1/Efemp2.
 IPR000742; EG-like_dom.
 IPR001881; EGF-like_Ca-bd.
 IPR013032; EGF-like_CS.
 IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
 IPR018097; EGF_Ca-bd_CS. 

Pfam

 PF07645; EGF_CA 

SMART

 SM00179; EGF_CA 

PROSITE

 PS00010; ASX_HYDROXYL
 PS01186; EGF_2
 PS50026; EGF_3
 PS01187; EGF_CA 

PRINTS