UniProt Accession

 D3Z0B4_MOUSE; D3Z0B4 

Genbank Protein ID

 AC142101 

Genbank Nucleotide ID

  

Protein Name

 Delta-1-pyrroline-5-carboxylate synthase 

Protein Synonyms/Alias

  

Gene Name

 Aldh18a1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
124	SGAVAFGKQRLRHEI	acetylation	[1, 2]

Reference

 [1] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 173 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0004349; F:glutamate 5-kinase activity; IDA:MGI.
 GO:0004350; F:glutamate-5-semialdehyde dehydrogenase activity; IEA:Compara.
 GO:0008652; P:cellular amino acid biosynthetic process; TAS:MGI.
 GO:0019240; P:citrulline biosynthetic process; IEA:Compara.
 GO:0006536; P:glutamate metabolic process; IEA:Compara.
 GO:0006592; P:ornithine biosynthetic process; IEA:Compara.
 GO:0006561; P:proline biosynthetic process; IEA:Compara. 

Interpro

 IPR001048; Asp/Glu/Uridylate_kinase.
 IPR001057; Glu/AcGlu_kinase. 

Pfam

 PF00696; AA_kinase 

SMART

  

PROSITE

  

PRINTS

 PR00474; GLU5KINASE.