UniProt Accession

 BRK1_MOUSE; Q91VR8; Q3TLB8 

Genbank Protein ID

 AK020128; AK150689; AK163236; AK166585; BC010582 

Genbank Nucleotide ID

 BAC25616.1; BAE29768.1; BAE37248.1; BAE38874.1; AAH10582.1 

Protein Name

 Protein BRICK1 

Protein Synonyms/Alias

 BRK1 

Gene Name

 Brk1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
30	EIITSSIKKISDFLN	ubiquitination	[1]
31	IITSSIKKISDFLNS	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine (By similarity).  

Keyword

 Acetylation; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 75 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
 GO:0030036; P:actin cytoskeleton organization; IMP:MGI.
 GO:0048870; P:cell motility; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0008284; P:positive regulation of cell proliferation; IMP:MGI. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS