CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043440
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 PDP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
94RAGETTHKILDLESRubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 242 AA 
Protein Sequence
MSSTVSYWIL NSTRNSIATL QGGRRLYSRY VSNRNKLKWR LFSRVPPTLN SSPCGGFTLC 60
KAYRHTSTEE DDFHLQLSPE QINEVLRAGE TTHKILDLES RVPNSVLRFE SNQLAANSPV 120
EDRRGVASCL QTNGLMFGIF DGHGGHACAQ AVSERLFYYV AVSLMSHQTL EHMEGAMESM 180
KPLLPILHWL KHPGDSIYKD VTSVHLDHLR VYWQELLDLH MEMGLSIEEA LMYSFQRLDS 240
DI 242 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0004741; F:[pyruvate dehydrogenase (lipoamide)] phosphatase activity; IEA:Compara.
 GO:0004724; F:magnesium-dependent protein serine/threonine phosphatase activity; IEA:Compara.
 GO:0035970; P:peptidyl-threonine dephosphorylation; IEA:Compara. 
Interpro
 IPR001932; PP2C-like.
 IPR000222; PP2C_Mn2_Asp60_BS.
 IPR015655; Protein_Pase_2C. 
Pfam
  
SMART
  
PROSITE
 PS01032; PP2C 
PRINTS