CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026342
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable ATP-dependent RNA helicase DHX35 
Protein Synonyms/Alias
  
Gene Name
 DHX35 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
115DQLATRIKFLTDGMLubiquitination[1]
134MVDPLLTKYSVIMLDubiquitination[1]
159IAIGLLKKIQKKRGDubiquitination[1]
180SATLDADKFRDFFNQubiquitination[1]
291LPSFEQMKVFERVSRubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 302 AA 
Protein Sequence
VGPVKFWRPG TEGPGVSISE ERQSLAENSG TTVVYNPYAA LSIEQQRQKL PVFKYLAEAG 60
WTAEGRVVGV TQPRRVAAVT VAGRVAEERG AVLGHEVGYC IRFDDCTDQL ATRIKFLTDG 120
MLVREMMVDP LLTKYSVIML DEAHERTLYT DIAIGLLKKI QKKRGDLRLI VASATLDADK 180
FRDFFNQNET SDPARDTCVI LTVEGRTFPV DIFYLQSPVP DYIKSTVETV VKIHQTEGDG 240
DVLAFLTGQE EVETVVSMLI EQARALARTG MKRHLRVLPM YAGLPSFEQM KVFERVSRSV 300
RK 302 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR002464; DNA/RNA_helicase_DEAH_CS.
 IPR014001; Helicase_ATP-bd.
 IPR027417; P-loop_NTPase. 
Pfam
  
SMART
 SM00487; DEXDc 
PROSITE
 PS00690; DEAH_ATP_HELICASE
 PS51192; HELICASE_ATP_BIND_1 
PRINTS