UniProt Accession

 NO40_MOUSE; Q9ESX4 

Genbank Protein ID

 AJ272345; AY253297; BC018382; BC049231 

Genbank Nucleotide ID

 CAC03718.1; AAO83392.1; AAH18382.1; AAH49231.1 

Protein Name

 Nucleolar protein of 40 kDa 

Protein Synonyms/Alias

 pNO40; Putative S1 RNA-binding domain protein; PS1D protein; Zinc finger CCHC domain-containing protein 17 

Gene Name

 Zcchc17 

Gene Synonyms/Alias

 Ps1d; Ldc4 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
144	GCKGHFAKDCFMQPG	acetylation	[1, 2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

 DOMAIN 16 88 S1 motif.
 ZN_FING 131 148 CCHC-type.
 MOD_RES 114 114 Phosphoserine (By similarity).  

Keyword

 Alternative splicing; Complete proteome; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Ribonucleoprotein; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 241 AA 

Protein Sequence

Gene Ontology

 GO:0022625; C:cytosolic large ribosomal subunit; IDA:MGI.
 GO:0005730; C:nucleolus; IDA:MGI.
 GO:0003723; F:RNA binding; TAS:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 

Interpro

 IPR012340; NA-bd_OB-fold.
 IPR003029; Rbsml_prot_S1_RNA-bd_dom.
 IPR022967; RNA-binding_domain_S1.
 IPR001878; Znf_CCHC. 

Pfam

 PF00575; S1 

SMART

 SM00316; S1
 SM00343; ZnF_C2HC 

PROSITE

 PS50126; S1
 PS50158; ZF_CCHC 

PRINTS