| Tag | Content |
|---|
| CPLM ID | CPLM-018886 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Peroxisomal membrane protein PEX13 |
Protein Synonyms/Alias | Peroxin-13 |
Gene Name | PEX13 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 304 | DMLNLALKEQQPKVR | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins. |
Sequence Annotation | DOMAIN 276 334 SH3.
REGION 145 233 Targeting to peroxisomes.
REGION 175 196 Interaction with PEX19. |
Keyword | Complete proteome; Disease mutation; Membrane; Peroxisome; Peroxisome biogenesis disorder; Protein transport; Reference proteome; SH3 domain; Transmembrane; Transmembrane helix; Transport; Zellweger syndrome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 403 AA |
Protein Sequence | MASQPPPPPK PWETRRIPGA GPGPGPGPTF QSADLGPTLM TRPGQPALTR VPPPILPRPS 60
QQTGSSSVNT FRPAYSSFSS GYGAYGNSFY GGYSPYSYGY NGLGYNRLRV DDLPPSRFVQ 120
QAEESSRGAF QSIESIVHAF ASVSMMMDAT FSAVYNSFRA VLDVANHFSR LKIHFTKVFS 180
AFALVRTIRY LYRRLQRMLG LRRGSENEDL WAESEGTVAC LGAEDRAATS AKSWPIFLFF 240
AVILGGPYLI WKLLSTHSDE VTDSINWASG EDDHVVARAE YDFAAVSEEE ISFRAGDMLN 300
LALKEQQPKV RGWLLASLDG QTTGLIPANY VKILGKRKGR KTVESSKVSK QQQSFTNPTL 360
TKGATVADSL DEQEAAFESV FVETNKVPVA PDSIGKDGEK QDL 403 |
Gene Ontology | GO:0005779; C:integral to peroxisomal membrane; IDA:UniProtKB. GO:0021795; P:cerebral cortex cell migration; ISS:UniProtKB. GO:0001561; P:fatty acid alpha-oxidation; ISS:UniProtKB. GO:0007626; P:locomotory behavior; ISS:UniProtKB. GO:0060152; P:microtubule-based peroxisome localization; ISS:UniProtKB. GO:0001764; P:neuron migration; ISS:UniProtKB. GO:0016560; P:protein import into peroxisome matrix, docking; IMP:UniProtKB. GO:0001967; P:suckling behavior; ISS:UniProtKB. |
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