CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040096
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase UBR3 
Protein Synonyms/Alias
  
Gene Name
 Ubr3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
300EKYLIALKSSGLTYPubiquitination[1]
367VKLSSGTKDQSIMDVubiquitination[1]
643YYAMFLSKAVKCQELubiquitination[1]
1044LVAERRKKFQEIINRubiquitination[1]
1140AVERILLKAAVQSRMubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1892 AA 
Protein Sequence
MAAAAAAAAV GDPQPPQPEA PAQGLALDKA ATAAHLKAAL SRPDNRAGAE ELQALLERVL 60
NAERPLAGAA GGEEAAGGGG GGPGEAEEDA LEWCKCLLAG GGGYEEFCAA VRAYDPAALC 120
GLVWTANFVA YRCRTCGISP CMSLCAECFH QGDHTGHDFN MFRSQAGGAC DCGDSNVMRE 180
SGFCRRHQIK SSSNIPCVPK DLLMMSEFVL PRFIFCLIQY LREGYNEPAD APSEKDLNKV 240
LQLLEPQISF LEDLTKMGGA MRSVLTQVLT NQQNYKDLTA GLGENACAKK SHEKYLIALK 300
SSGLTYPEDK LVYGVQEPAA GTSTLAAQGF AGATGTLGQI DSSDEEDQDG SQGLGKRKRV 360
KLSSGTKDQS IMDVLKHKSF LEELLFWTIK YEFPQKMVTF LLNMLPDQEY KVAFTKTFVQ 420
HYAFIMKTLK KSHESDTMSN RIVHISVQLF SNEELARQVT EECQLLDIMV TVLLYMMESC 480
LIKSELQDEE NSLHVVVNCG EALLKNNTYW PLVSDFINIL SHQSVAQRFL EDHGLLVTWM 540
NFVSFFQGMN LNKRELNEHV EFESQTYYAA FAAELEACAQ PMWGLLSHCK VRETQEYTRN 600
VVRYCLEALQ DWFDAINFVD EPAPNQVTFH LPLHRYYAMF LSKAVKCQEL DLDSLLPDQE 660
MLMKLMIHPL QIQASLAEIH SNMWVRNGLQ IKGQAMTYVQ SHFCNSMIDP DIYLLQVCAS 720
RLDPDYFISS VFERFKVVDL LTMASQHHNM VLDVEHERSM LEGALTFLVI LLSLRLHLGM 780
SDDDILRAEM VAQLCMNDRT HSSLLDLIPE NPNPKSGIIP GSYSFESVLS AVADFRAPIF 840
EPGGSMQQGM YTPKAEVWDQ EFDPVMVILR TVYRRDVQSA MDRYTAFLKQ SGKFPGNPWP 900
PYKKRTSLHP SYKGLMRLLH CKTLHIVLFT LLYKILMDHQ NLSEHVLCMV LYLIELGLEN 960
SADDDSEEEV SMGGPERCHD SWFPGSNLVS NMRHFINYVR VRVPETAPEL KRDPLASTSS 1020
DALDSLQNSG TAQVFSLVAE RRKKFQEIIN RSNSEANQVV RPKIPSKWSA PGSSPQLTTA 1080
ILEIKESILS LLIKLHHKLS GKQNSYYPPW LDDIEVLIQP EIPKYNHGDG ITAVERILLK 1140
AAVQSRMNKR IIEEICRKVT PPVPPKKITA AEKKTLDKEE RRQKARERQQ KLLAEFASRQ 1200
KSFMETAMDV DSPENDIPME ITTAEPQVSE AVYDCVICGQ SGPSSEDRPT GLVVLLQASS 1260
VLGQCRDNAE PKKLPIAEEE QIYPWDTCAA VHDVRLSLLQ RYFKDSSCLL AVSIGWEGGV 1320
YVQTCGHTLH IDCHKSYMES LRNDQVLQGF SVDKGEFTCP LCRQFANSVL PCYPGSNVEN 1380
NLWQRPCNKS TQDLIKEVEE LQGRPGAFPV SISSETNLSK EMESVMKDIK NTTQKKYRDY 1440
SKTPGSPDNE FLFMYSVART NLELELIHRG GSLCSGGPST AGKRSCLNQL FHVLALHMRL 1500
YTIDSEYNPW KKLTQLVEDM NSQVGNEDQQ PEVPILYHDV TSLLLIQILM MPQPLRKEHF 1560
TCIVKVLFTL LYTQALAALS VKGTEEDRSA WKHAGALRKD TCDAEKCYEV LLSFVISELS 1620
KGKLYYEEGA QECAMVSPIA WSPESMERYI QDFCLPFLRV SSLLQHHLFG EDLPSCQEEE 1680
EFSVLASCLG LLPTFYQTDH PFISASCLDW PVAAFDIITQ WCFEITSFTE RHAEQGKALL 1740
IQESRWKLPH LLQLPENYNT IFQYYHRKTC SVCTKVPKDP AVCLVCGTFV CLKGLCCKQQ 1800
SYCECVLHSQ NCGAGTGIFL LINASVIIII RGHRFCLWGS VYLDAHGEED RDLRRGKPLY 1860
ICEERYRVLE QQWVSHTFDH INKRWGPHYN GL 1892 
Gene Ontology
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0042048; P:olfactory behavior; IMP:MGI.
 GO:0016567; P:protein ubiquitination; IEA:GOC.
 GO:0001967; P:suckling behavior; IMP:MGI. 
Interpro
 IPR003126; Znf_N-recognin. 
Pfam
 PF02207; zf-UBR 
SMART
  
PROSITE
 PS51157; ZF_UBR 
PRINTS