CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030661
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine/threonine-protein kinase 33 
Protein Synonyms/Alias
 cDNA FLJ58445, highly similar to Serine/threonine-protein kinase 33 (EC 2.7.11.1) 
Gene Name
 STK33 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
59RGNFTEGKVPHIRIEubiquitination[1]
117KAGSSAVKLLEREVNubiquitination[1]
199DIVHRDLKLENIMVKubiquitination[1]
230TDFGLAVKKQSRSEAubiquitination[1]
332PAHRITAKELLDNQWubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 473 AA 
Protein Sequence
MSQTSSIGSA ESLISLERKK EKNINRDITS RKDLPSRTSN VERKASQQQW GRGNFTEGKV 60
PHIRIENGAA IEEIYTFGRI LGKGSFGIVI EATDKETETK WAIKKVNKEK AGSSAVKLLE 120
REVNILKSVK HEHIIHLEQV FETPKKMYLV MELCEDGELK EILDRKGHFS ENETRWIIQS 180
LASAIAYLHN NDIVHRDLKL ENIMVKSSLI DDNNEINLNI KVTDFGLAVK KQSRSEAMLQ 240
ATCGTPIYMA PEVISAHDYS QQCDIWSIGV VMYMLLRGEP PFLASSEEKL FELIRKGELH 300
FENAVWNSIS DCAKSVLKQL MKVDPAHRIT AKELLDNQWL TGNKLSSVRP TNVLEMMKEW 360
KNNPESVEEN TTEEKNKPST EEKLKSYQPW GNVPDANYTS DEEEEKQSTA YEKQFPATSK 420
DNFDMCSSSF TSSKLLPAEI KGEMEKTPVT PSQGTATKYP AKSGALSRTK KKL 473 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
 GO:0046777; P:protein autophosphorylation; IEA:Compara. 
Interpro
 IPR020636; Ca/CaM-dep_Ca-dep_prot_Kinase.
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00069; Pkinase 
SMART
 SM00220; S_TKc 
PROSITE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS