UniProt Accession

 ITM2A_HUMAN; O43736; B2R7X5; B4E062 

Genbank Protein ID

 AF038953; AY359051; AK303238; AK313154; AL009028; AL021786; AL021786; AL009028; CH471104; BC040437 

Genbank Nucleotide ID

 AAC39867.1; AAQ89410.1; BAG64324.1; BAG35972.1; CAI42363.1; CAI42363.1; CAI43020.1; CAI43020.1; EAW98591.1; AAH40437.1 

Protein Name

 Integral membrane protein 2A 

Protein Synonyms/Alias

 Protein E25 

Gene Name

 ITM2A 

Gene Synonyms/Alias

 UNQ603/PRO1189 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
37	RTQILTGKSTIYRGE	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

 DOMAIN 133 227 BRICHOS.
 CARBOHYD 166 166 N-linked (GlcNAc...) (Potential).  

Keyword

 Alternative splicing; Complete proteome; Glycoprotein; Membrane; Polymorphism; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 263 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 

Interpro

 IPR007084; BRICHOS_dom. 

Pfam

 PF04089; BRICHOS 

SMART

 SM01039; BRICHOS 

PROSITE

 PS50869; BRICHOS 

PRINTS