CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017926
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein phosphatase 1 regulatory subunit 35 
Protein Synonyms/Alias
  
Gene Name
 PPP1R35 
Gene Synonyms/Alias
 C7orf47 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
128GSHFDAAKAVEEQLRubiquitination[1]
182LNAALREKLALLPPQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Inhibits PPP1CA phosphatase activity. 
Sequence Annotation
 MOD_RES 47 47 Phosphoserine.
 MOD_RES 52 52 Phosphoserine.  
Keyword
 Complete proteome; Phosphoprotein; Protein phosphatase inhibitor; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 253 AA 
Protein Sequence
MMMGCGESEL KSADGEEAAA VPGPPPEPQV PQLRAPVPEP GLDLSLSPRP DSPQPRHGSP 60
GRRKGRAERR GAARQRRQVR FRLTPPSPVR SEPQPAVPQE LEMPVLKSSL ALGLELRAAA 120
GSHFDAAKAV EEQLRKSFQI RCGLEESVSE GLNVPRSKRL FRDLVSLQVP EEQVLNAALR 180
EKLALLPPQA RAPHPKEPPG PGPDMTILCD PETLFYESPH LTLDGLPPLR LQLRPRPSED 240
TFLMHRTLRR WEA 253 
Gene Ontology
 GO:0019902; F:phosphatase binding; IDA:UniProtKB.
 GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
 GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS