UniProt Accession

 B4DHQ3_HUMAN; B4DHQ3 

Genbank Protein ID

 AK295222 

Genbank Nucleotide ID

 BAG58215.1 

Protein Name

 cDNA FLJ56437, highly similar to Phosphoserine aminotransferase (EC 2.6.1.52) 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
61	NFGPGPAKLPHSVLL	ubiquitination	[1]
72	SVLLEIQKELLDYKG	ubiquitination	[1]
96	HRSSDFAKIINNTEN	ubiquitination	[1, 2, 3]
235	SKPVDVSKFGVIFAG	ubiquitination	[1]
363	KGDDALEKRFLDKAL	ubiquitination	[2]
368	LEKRFLDKALELNML	ubiquitination	[1, 2, 3]
378	ELNMLSLKGHRSVGG	ubiquitination	[1, 2, 3]
408	KLAAFMKKFLEMHQL	ubiquitination	[1]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Amino-acid biosynthesis; Aminotransferase; Serine biosynthesis; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 415 AA 

Protein Sequence

Gene Ontology

 GO:0004648; F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity; IEA:InterPro.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. 

Interpro

 IPR000192; Aminotrans_V/Cys_dSase.
 IPR020578; Aminotrans_V_PyrdxlP_BS.
 IPR022278; Pser_aminoTfrase.
 IPR003248; Pser_aminoTfrase_subgr.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 

Pfam

 PF00266; Aminotran_5 

SMART

  

PROSITE

 PS00595; AA_TRANSFER_CLASS_5 

PRINTS