UniProt Accession

 G3X981_MOUSE; G3X981 

Genbank Protein ID

 AC157610; CH466550 

Genbank Nucleotide ID

 EDL04148.1 

Protein Name

 Peripherin 

Protein Synonyms/Alias

 Peripherin 1, isoform CRA_b 

Gene Name

 Prph 

Gene Synonyms/Alias

 Prph1; mCG_18385 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
292	QEAEEWYKSKVREHW	acetylation	[1, 2]
292	QEAEEWYKSKVREHW	ubiquitination	[3]
434	IEIATYRKLLEGEES	acetylation	[1, 2]
434	IEIATYRKLLEGEES	ubiquitination	[3]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Coiled coil; Complete proteome; Intermediate filament; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 507 AA 

Protein Sequence

Gene Ontology

 GO:0044299; C:C-fiber; IDA:MGI.
 GO:0005883; C:neurofilament; IDA:MGI.
 GO:0043025; C:neuronal cell body; ISO:MGI.
 GO:0042622; C:photoreceptor outer segment membrane; IDA:MGI.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0045104; P:intermediate filament cytoskeleton organization; IDA:MGI. 

Interpro

 IPR016044; F.
 IPR001664; IF.
 IPR006821; Intermed_filament_DNA-bd.
 IPR018039; Intermediate_filament_CS. 

Pfam

 PF00038; Filament
 PF04732; Filament_head 

SMART

  

PROSITE

 PS00226; IF 

PRINTS