CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032270
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 C11orf30 protein 
Protein Synonyms/Alias
 Protein EMSY 
Gene Name
 C11orf30 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
243KAVVPVSKTITVPVSubiquitination[1]
401STRLPSPKSLVSAPTubiquitination[2]
423KQHQQSPKQQLYQVQubiquitination[2]
567SLATLGGKIISSNIVubiquitination[2]
589TTIPMTSKPNVIVVQubiquitination[1, 2]
597PNVIVVQKTTGKGTTubiquitination[2]
601VVQKTTGKGTTIQGLubiquitination[1, 2]
611TIQGLPGKNVVTTLLubiquitination[1, 2, 3, 4]
624LLNAGGEKTIQTVPTubiquitination[1, 2]
634QTVPTGAKPAILTATacetylation[1]
634QTVPTGAKPAILTATubiquitination[1, 2]
653KMIVTQPKGIGSTVQubiquitination[1, 2, 4]
664STVQPAAKIIPTKIVubiquitination[1, 2]
669AAKIIPTKIVYGQQGubiquitination[1, 2, 4]
683GKTQVLIKPKPVTFQubiquitination[2]
859LTQSQSAKQQKLSQPubiquitination[1, 2, 3]
862SQSAKQQKLSQPPLEubiquitination[1, 2, 3]
876EQTQLQVKTLQCFQTubiquitination[2]
912QLSIRHQKLTPLQQEubiquitination[2]
937TQHPMVAKDRQLPTLubiquitination[1, 2]
1052SPIQASEKTAVSDILubiquitination[1, 2]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1231 AA 
Protein Sequence
MPVVWPTLLD LSRDECKRIL RKLELEAYAG VISALRAQGD LTKEKKDLLG ELSKVLSIST 60
ERHRAEVRRA VNDERLTTIA HKMNLSLYLG ERPSYSMSGP NSSSEWSIEG RRLVPLMPRL 120
VPQTAFTVTA NAVANAAIQH NASLPVPAET GSKEVVCYSY TSTTSTPTST PVPSGSIATV 180
KSPRPASPAS NVVVLPSGST VYVKSVSCSD EDEKPRKRRR TNSSSSSPVV LKEVPKAVVP 240
VSKTITVPVS GSPKMSNIMQ SIANSLPPHM SPVKITFTKP STQTTNTTTQ KVIIVTTSPS 300
STFVPNILSK SHNYAAVTKL VPTSVIASTT QKPPVVITAS QSSLVSNSSS GSSSSTPSPI 360
PNTVAVTAVV SSTPSVVMST VAQGVSTSAI KMASTRLPSP KSLVSAPTQI LAQFPKQHQQ 420
SPKQQLYQVQ QQTQQQVAQP SPVSHQQQPQ QSPLPPGIKP TIQIKQESGV KIITQQVQPS 480
KILPKPVTAT LPTSSNSPIM VVSSNGAIMT TKLVTTPTGT QATYTRPTVS PSIGRMAATP 540
GAATYVKTTS GSIITVVPKS LATLGGKIIS SNIVSGTTTK ITTIPMTSKP NVIVVQKTTG 600
KGTTIQGLPG KNVVTTLLNA GGEKTIQTVP TGAKPAILTA TRPITKMIVT QPKGIGSTVQ 660
PAAKIIPTKI VYGQQGKTQV LIKPKPVTFQ ATVVSEQTRQ LVTETLQQAS RVAEAGNSSI 720
QEGKEEPQNY TDSSSSSTES SQSSQDAVVI SGEISSPPLF SVSHRSQPQQ PSQPQRTLLQ 780
HVAQSQTATQ TSVVVKSIPA SSPGAITHIM QQALSSHTAF TKHSEELGTE EGEVEEMDTL 840
DPQTGLFYRS ALTQSQSAKQ QKLSQPPLEQ TQLQVKTLQC FQTKQKQTIH LQADQLQHKL 900
PQMPQLSIRH QKLTPLQQEQ AQPKPDVQHT QHPMVAKDRQ LPTLMAQPPQ TVVQVLAVKT 960
TQQLPKLQQA PNQPKIYVQP QTPQSQMSLP ASSEKQTASQ VEQPIITQGS SVTKITFEGR 1020
QPPTVTKITG GSSVPKLTSP VTSISPIQAS EKTAVSDILK MSLMEAQIDT NVEHMIVDPP 1080
KKALATSMLT GEAGSLPSTH MVVAGMANST PQQQKCRESC SSPSTVGSSL TTRKIDPPAV 1140
PATGQFMRIQ NVGQKKAEES PAEIIIQAIP QYAIPCHSSS NVVVEPSGLL ELNNFTSQQL 1200
DDEETAMEQD IDSSTEDGTE PSPSQSSAER S 1231 
Gene Ontology
  
Interpro
 IPR005491; ENT_N. 
Pfam
 PF03735; ENT 
SMART
  
PROSITE
 PS51138; ENT 
PRINTS