CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025374
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Mmp3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
388LGLPATVKKIDAAISubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 ACT_SITE 221 221 By similarity.  
Keyword
 Calcium; Disulfide bond; Hydrolase; Metal-binding; Metalloprotease; Protease; Repeat; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 479 AA 
Protein Sequence
MKMKGLPVLL WLCVVVCSSY PLHDSARDDD AGMELLQKYL ENYYGLAKDV KQFIKKKDSS 60
LIVKKIQEMQ KFLGLEMTGK LDSNTMELMH KPRCGVPDVG GFSTFPGSPK WRKSHITYRI 120
VNYTPDLPRQ SVDSAIEKAL KVWEEVTPLT FSRISEGEAD IMISFAVGEH GDFVPFDGPG 180
TVLAHAYAPG PGINGDAHFD DDERRTEDVT GTNLFLVAAH ELGHSLGLYH SAKAEALMYP 240
VYKSSTDLSR FHLSQDDVDG IQSLYGTPTA SPDVLVVPTK SNSLEPETSP MCSSTLFFDA 300
VSTLRGEVLF FKDRHFWRKS LRTPEPEFYL ISSFWPSLPS NMDAAYEVTN RDTVFIFKGN 360
QFWAIRGHEE LAGYPKSIHT LGLPATVKKI DAAISNKEKR KTYFFVEDKY WRFDEKKQSM 420
EPGFPRKIAE DFPGVDSRVD AVFEAFGFLY FFSGSSQLEF DPNAKKVTHI LKSNSWFNC 479 
Gene Ontology
 GO:0031012; C:extracellular matrix; IEA:InterPro.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0071230; P:cellular response to amino acid stimulus; IDA:MGI.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
 GO:0030334; P:regulation of cell migration; IMP:MGI. 
Interpro
 IPR000585; Hemopexin-like_dom.
 IPR018487; Hemopexin-like_repeat.
 IPR018486; Hemopexin_CS.
 IPR024079; MetalloPept_cat_dom.
 IPR001818; Pept_M10_metallopeptidase.
 IPR021190; Pept_M10A.
 IPR016293; Pept_M10A_Metazoans.
 IPR021158; Pept_M10A_Zn_BS.
 IPR006026; Peptidase_Metallo.
 IPR002477; Peptidoglycan-bd-like. 
Pfam
 PF00045; Hemopexin
 PF00413; Peptidase_M10
 PF01471; PG_binding_1 
SMART
 SM00120; HX
 SM00235; ZnMc 
PROSITE
 PS00546; CYSTEINE_SWITCH
 PS00024; HEMOPEXIN 
PRINTS
 PR00138; MATRIXIN.