| Tag | Content |
|---|
| CPLM ID | CPLM-007332 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | S-formylglutathione hydrolase |
Protein Synonyms/Alias | FGH |
Gene Name | YJL068C; HRE299, J1102 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 181 | GYSGKRYKSCSAFAP | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Serine hydrolase involved in the detoxification of formaldehyde. |
Sequence Annotation | ACT_SITE 161 161 Charge relay system (By similarity).
ACT_SITE 241 241 Charge relay system (By similarity).
ACT_SITE 276 276 Charge relay system (By similarity). |
Keyword | 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Reference proteome; Serine esterase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 299 AA |
Protein Sequence | MKVVKEFSVC GGRLIKLSHN SNSTKTSMNV NIYLPKHYYA QDFPRNKRIP TVFYLSGLTC 60
TPDNASEKAF WQFQADKYGF AIVFPDTSPR GDEVANDPEG SWDFGQGAGF YLNATQEPYA 120
QHYQMYDYIH KELPQTLDSH FNKNGDVKLD FLDNVAITGH SMGGYGAICG YLKGYSGKRY 180
KSCSAFAPIV NPSNVPWGQK AFKGYLGEEK AQWEAYDPCL LIKNIRHVGD DRILIHVGDS 240
DPFLEEHLKP ELLLEAVKAT SWQDYVEIKK VHGFDHSYYF VSTFVPEHAE FHARNLGLI 299 |
Gene Ontology | GO:0005829; C:cytosol; IDA:SGD. GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. GO:0018738; F:S-formylglutathione hydrolase activity; IDA:SGD. GO:0046294; P:formaldehyde catabolic process; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |