CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030115
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SRY-box containing gene 5, isoform CRA_b 
Protein Synonyms/Alias
 Transcription factor SOX-5 
Gene Name
 Sox5 
Gene Synonyms/Alias
 mCG_13895 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
147ADVVDTLKQRKMEELubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 763 AA 
Protein Sequence
MLTDPDLPQE FERMSSKRPA SPYGETDGEV AMVTSRQKVE EEESERLPAF HLPLHVSFPN 60
KPHSEEFQPV SLLTQETCGP RTPTVQHNTM EVDGNKVMSS LAPYNSSTSP QKAEEGGRQS 120
GESVSSAALG TPERRKGSLA DVVDTLKQRK MEELIKNEPE DTPSIEKLLS KDWKDKLLAM 180
GSGNFGEIKG TPESLAEKER QLMGMINQLT SLREQLLAAH DEQKKLAASQ IEKQRQQMEL 240
AKQQQEQIAR QQQQLLQQQH KINLLQQQIQ VQGQLPPLMI PVFPPDQRTL AAAAQQGFLL 300
PPGFSYKAGC SDPYPVQLIP TTMAAAAAAT PGLGPLQLQQ FYAAQLAAMQ VSPGGKLLGL 360
PQGNLGAAVS PTSIHTDKST NSPPPKSKDE VAQPLNLSAK PKTSDGKSPA SPTSPHMPAL 420
RINSGAGPLK ASVPAALASP SARVSTIGYL NDHDAVTKAI QEARQMKEQL RREQQALDGK 480
VAVVNSIGLS NCRTEKEKTT LESLTQQLAV KQNEEGKFSH GMMDFNMSGD SDGSAGVSES 540
RIYRESRGRG SNEPHIKRPM NAFMVWAKDE RRKILQAFPD MHNSNISKIL GSRWKAMTNL 600
EKQPYYEEQA RLSKQHLEKY PDYKYKPRPK RTCLVDGKKL RIGEYKAIMR NRRQEMRQYF 660
NVGQQAQIPI ATAGVVYPSA IAMAGMPSPH LPSEHSSVSS SPEPGMPVIQ STYGAKGEEP 720
HIKEEIQAED INGEIYEEYD EEEEDPDVDY GSDSENHIAG QAN 763 
Gene Ontology
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
 GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
 GO:0051216; P:cartilage development; IGI:MGI.
 GO:0045165; P:cell fate commitment; IGI:MGI.
 GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Compara.
 GO:0021953; P:central nervous system neuron differentiation; IGI:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.
 GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.
 GO:0061036; P:positive regulation of cartilage development; IEA:Compara.
 GO:0032332; P:positive regulation of chondrocyte differentiation; IEA:Compara.
 GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0060164; P:regulation of timing of neuron differentiation; IMP:MGI. 
Interpro
 IPR009071; HMG_box_dom. 
Pfam
 PF00505; HMG_box 
SMART
 SM00398; HMG 
PROSITE
 PS50118; HMG_BOX_2 
PRINTS