UniProt Accession

 K1PF_ECOLI; P0AEW9; P23539 

Genbank Protein ID

 X53948; U00007; U00096; AP009048 

Genbank Nucleotide ID

 CAA37896.1; AAA60525.1; AAC75229.1; BAA15977.1 

Protein Name

 1-phosphofructokinase 

Protein Synonyms/Alias

 Fructose 1-phosphate kinase 

Gene Name

 fruK 

Gene Synonyms/Alias

 fpk; b2168; JW2155 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
32	RGEVNLVKTTGLHAA	acetylation	[1, 2]
41	TGLHAAGKGINVAKV	acetylation	[1, 2]
99	INVKLTEKDGEVTDF	acetylation	[2]
178	EALVAGLKAAPWLVK	acetylation	[2]
203	GRKLPEMKDVIEAAH	acetylation	[2]

Reference

 [1] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111]
 [2] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

  

Sequence Annotation

  

Keyword

 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 312 AA 

Protein Sequence

Gene Ontology

 GO:0008662; F:1-phosphofructokinase activity; IDA:EcoCyc.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0006001; P:fructose catabolic process; IMP:EcoCyc. 

Interpro

 IPR022463; 1-PFruKinase.
 IPR002173; Carboh/pur_kinase_PfkB_CS.
 IPR011611; PfkB_dom.
 IPR017583; Tagatose/fructose_Pkinase. 

Pfam

 PF00294; PfkB 

SMART

  

PROSITE

 PS00583; PFKB_KINASES_1
 PS00584; PFKB_KINASES_2 

PRINTS