| Tag | Content |
|---|
| CPLM ID | CPLM-015086 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | WD repeat-containing protein 44 |
Protein Synonyms/Alias | Rabphilin-11 |
Gene Name | Wdr44 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 673 | LSGSLDGKLRLWNIP | ubiquitination | [1] | | 758 | EPLPGENKILVTSND | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Downstream effector for RAB11. May be involved in vesicle recycling (By similarity). |
Sequence Annotation | REPEAT 511 550 WD 1.
REPEAT 607 645 WD 2.
REPEAT 647 687 WD 3.
REPEAT 692 731 WD 4.
REPEAT 742 781 WD 5.
REPEAT 786 825 WD 6.
REPEAT 840 880 WD 7.
REPEAT 882 915 WD 8.
REGION 2 173 Binding activity.
MOD_RES 2 2 N-acetylalanine (By similarity).
MOD_RES 3 3 Phosphoserine (By similarity).
MOD_RES 11 11 Phosphotyrosine (By similarity).
MOD_RES 27 27 Phosphoserine (By similarity).
MOD_RES 50 50 Phosphoserine (By similarity).
MOD_RES 221 221 Phosphothreonine (By similarity).
MOD_RES 264 264 Phosphoserine.
MOD_RES 273 273 Phosphothreonine (By similarity).
MOD_RES 344 344 Phosphoserine (By similarity).
MOD_RES 346 346 Phosphoserine.
MOD_RES 351 351 Phosphothreonine.
MOD_RES 405 405 Phosphoserine.
MOD_RES 472 472 Phosphoserine.
MOD_RES 473 473 Phosphoserine.
MOD_RES 474 474 Phosphoserine.
MOD_RES 563 563 Phosphoserine (By similarity).
MOD_RES 567 567 Phosphoserine (By similarity). |
Keyword | Acetylation; Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Endosome; Golgi apparatus; Membrane; Phosphoprotein; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 915 AA |
Protein Sequence | MASESDTEEF YDAPEDVHLG TGYPVGSPGK VGLLSFKEAE NTANQAGNES PVQELRQDVS 60
KKIIESIIEE SQKVLQLEDD SLDSKGKGLS DEATAGPSVA GTEFSNIPGL LAIEHELQQD 120
SEKAESQNVA EESELETQKC FPSDETCEKS EKTVDETDNL TEVSSGEQLD ASGLEAETLN 180
KEALEVKEGD VLDPASLDTL STTDFAAVEE VAPAKPPRHL TPEPDIVAST KKPVPARPPP 240
PTNFPPPRPP PPSRPAPPPR KKKSELEFEA LKTPDLDVPK ENITSDSLLT TNMASENTVR 300
DSLPSLDLAS ATSGDKIVTA QENGKAPDVQ TVAGEVMGPQ RPRSNSGREL TDEEILASVM 360
IKNLDTGEEI PLSLAEEKLP TGINPLTLHI MRRTKEYVSN DATQSDDEEK LQSQQTDTDG 420
GRLKQKTTQL KKFLGKSVKR AKHLAEEYGE RAINKVKSVR DEVFHTDQDD PSSSDDEGMP 480
YTRPVKFKAA HGFKGPYDFD QIKVVQDLSG EHMGAVWTMK FSHCGRLLAS AGQDNIVRIW 540
ALKNAFDYFN NMRMKYNTEG RVSPSPSQES LSSSKSDTDM GVCSGTDEDP DDKNAPFRQR 600
PFCKYKGHTA DLLDLSWSKN YFLLSSSMDK TVRLWHISRR ECLCCFQHID FVTAIAFHPR 660
DDRYFLSGSL DGKLRLWNIP DKKVALWNEV DGQTKLITAA NFCQNGKYAV IGTYDGRCIF 720
YDTEHLKYHT QIHVRSTRGR NKVGRKITGI EPLPGENKIL VTSNDSRIRL YDLRDLSLSM 780
KYKGYVNSSS QIKASFSHDF TYLVSGSEDK YVYIWSTYHD LSKFTSVRRD RNDFWEGIKA 840
HNAVVTSAIF APNPSLMLSL DVQSEKLEGI DKYEDAEVLD STSTGIVKTD NTEVLLSADF 900
TGAIKVFINK RKTVS 915 |
Gene Ontology | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |