| Tag | Content |
|---|
| CPLM ID | CPLM-002431 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein UshA |
Protein Synonyms/Alias | UDP-sugar hydrolase; UDP-sugar diphosphatase; UDP-sugar pyrophosphatase; 5'-nucleotidase; 5'-NT |
Gene Name | ushA |
Gene Synonyms/Alias | b0480; JW0469 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 153 | STGERLFKPWALFKR | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Degradation of external UDP-glucose to uridine monophosphate and glucose-1-phosphate, which can then be used by the cell. |
Sequence Annotation | REGION 375 379 Substrate binding.
REGION 498 504 Substrate binding.
METAL 41 41 Zinc 1.
METAL 43 43 Zinc 1.
METAL 84 84 Zinc 1.
METAL 84 84 Zinc 2.
METAL 116 116 Zinc 2.
METAL 217 217 Zinc 2.
METAL 252 252 Zinc 2.
METAL 254 254 Zinc 1.
DISULFID 258 275 |
Keyword | 3D-structure; Complete proteome; Direct protein sequencing; Disulfide bond; Hydrolase; Metal-binding; Nucleotide-binding; Periplasm; Reference proteome; Signal; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 550 AA |
Protein Sequence | MKLLQRGVAL ALLTTFTLAS ETALAYEQDK TYKITVLHTN DHHGHFWRNE YGEYGLAAQK 60
TLVDGIRKEV AAEGGSVLLL SGGDINTGVP ESDLQDAEPD FRGMNLVGYD AMAIGNHEFD 120
NPLTVLRQQE KWAKFPLLSA NIYQKSTGER LFKPWALFKR QDLKIAVIGL TTDDTAKIGN 180
PEYFTDIEFR KPADEAKLVI QELQQTEKPD IIIAATHMGH YDNGEHGSNA PGDVEMARAL 240
PAGSLAMIVG GHSQDPVCMA AENKKQVDYV PGTPCKPDQQ NGIWIVQAHE WGKYVGRADF 300
EFRNGEMKMV NYQLIPVNLK KKVTWEDGKS ERVLYTPEIA ENQQMISLLS PFQNKGKAQL 360
EVKIGETNGR LEGDRDKVRF VQTNMGRLIL AAQMDRTGAD FAVMSGGGIR DSIEAGDISY 420
KNVLKVQPFG NVVVYADMTG KEVIDYLTAV AQMKPDSGAY PQFANVSFVA KDGKLNDLKI 480
KGEPVDPAKT YRMATLNFNA TGGDGYPRLD NKPGYVNTGF IDAEVLKAYI QKSSPLDVSV 540
YEPKGEVSWQ 550 |
Gene Ontology | GO:0030288; C:outer membrane-bounded periplasmic space; IMP:EcoCyc. GO:0008253; F:5'-nucleotidase activity; IDA:EcoCyc. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. GO:0008768; F:UDP-sugar diphosphatase activity; IDA:EcoCyc. GO:0009166; P:nucleotide catabolic process; IGI:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |