CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035183
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Tesc 
Protein Synonyms/Alias
  
Gene Name
 Tesc 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
44GDQPTIRKENFNNVPubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 214 AA 
Protein Sequence
MGAAHSASEE VRELEGKTGF SSDQIEQLHR RFKQLSGDQP TIRKENFNNV PDLELNPIRS 60
KIVRAFFDNR NLRKGSSGLA DEINFEDFLT IMSYFRPIDT TLGEEQVELS RKEKLKFLFH 120
MYDSDSDGRI TLEEYRNVVE ELLSGNPHIE KESARSIADG AMMEAASVCV GQMEPDQVYE 180
GITFEDFLKI WQGIDIETKM HIRFLNMETI ALCH 214 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0030027; C:lamellipodium; ISS:UniProtKB.
 GO:0005634; C:nucleus; ISS:UniProtKB.
 GO:0005886; C:plasma membrane; ISS:UniProtKB.
 GO:0001726; C:ruffle; IEA:Compara.
 GO:0005509; F:calcium ion binding; ISS:UniProtKB.
 GO:0000287; F:magnesium ion binding; IEA:Compara.
 GO:0019212; F:phosphatase inhibitor activity; IEA:Compara.
 GO:0071300; P:cellular response to retinoic acid; IEA:Compara.
 GO:0008584; P:male gonad development; IEA:Compara.
 GO:0030219; P:megakaryocyte differentiation; IEA:Compara.
 GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
 GO:0030854; P:positive regulation of granulocyte differentiation; IEA:Compara.
 GO:0045654; P:positive regulation of megakaryocyte differentiation; ISS:UniProtKB.
 GO:0032417; P:positive regulation of sodium:hydrogen antiporter activity; IEA:Compara.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.
 GO:0051604; P:protein maturation; IEA:Compara.
 GO:0050821; P:protein stabilization; IEA:Compara.
 GO:0072661; P:protein targeting to plasma membrane; IEA:Compara.
 GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 
Pfam
 PF13405; EF_hand_4 
SMART
  
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS