CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008550
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dolichyl-phosphate-mannose--protein mannosyltransferase 5 
Protein Synonyms/Alias
  
Gene Name
 PMT5 
Gene Synonyms/Alias
 YDL093W; D2399 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
18PIPDVTIKRGPLRSFubiquitination[1]
29LRSFLITKPCDNLSSubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins (By similarity). 
Sequence Annotation
 DOMAIN 320 374 MIR 1.
 DOMAIN 384 444 MIR 2.
 DOMAIN 454 510 MIR 3.
 CARBOHYD 33 33 N-linked (GlcNAc...) (Potential).
 CARBOHYD 213 213 N-linked (GlcNAc...) (Potential).
 CARBOHYD 380 380 N-linked (GlcNAc...) (Potential).
 CARBOHYD 386 386 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Endoplasmic reticulum; Glycoprotein; Glycosyltransferase; Membrane; Reference proteome; Repeat; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 743 AA 
Protein Sequence
MNKEHLLKVD PIPDVTIKRG PLRSFLITKP CDNLSSLRTV TSSKEKLLVG CLLIFTAIVR 60
LHNISLPNSV VFGENEVGTF VSQYVNNIFF TDVHPPLVAM LYATVSSVFG YKGLFNYGNI 120
GTEYTANVPY VAMRFFSATL GIVSVLVLYL TLRVSGVKIA VAAICAVCFA IENSFVTLSR 180
FTLIEGPFVF FMACAVYFFR RSELYLPNSC KANKSLLAAS IALGFAVSSK WAGLFTIAWA 240
GIIVLWRVWF MIGDLSRPIG SSIKYMAFQF TCLLAIPAFI YFLIFSVHIK TLNVNGISSS 300
FFPAEFRKTL KYNNVIKETV AEVAVGSAVS LNHVGTAGGY LHSHLHNYPA GSMQQQVTLY 360
PHIDQNNKWI IELAEHPNEN VTSFQNLTDG TIIKLRQLKN GCRLHSHDHK PPVSQNADWQ 420
KEVSCYGYEG FEGDINDDWI IEIDKKRSEP GPAQEHIRAI ETKFRLKHYL TGCYLFSHPE 480
KLPEWGFGQQ EVTCAYFARE DLTSWYIEEN ENEISLPNPE KVSYKKMSFW QKFVAIHKFM 540
FYLNNYMDTS HAYSSEPKTW PLMLRGIDFW NENGREVYFL GNAVLWWSVT AFICTFIIGV 600
AVELLAWKLG VNILRDKHII NFHYQVFQYL LGFAAHYFPY FFVGQKLFLY DYLPAYYFGI 660
LAFGHALDLI STYISNKRNN TGYIVVAIFM VVCFYFFSEH SPLIYATGWS SNLCKRSKWL 720
GSWDFYCNSL LLSDSHYELN AES 743 
Gene Ontology
 GO:0031502; C:dolichyl-phosphate-mannose-protein mannosyltransferase complex; IPI:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0004169; F:dolichyl-phosphate-mannose-protein mannosyltransferase activity; ISS:SGD.
 GO:0035269; P:protein O-linked mannosylation; ISS:SGD. 
Interpro
 IPR027005; GlyclTrfase_39_like.
 IPR003342; Glyco_trans_39.
 IPR016093; MIR_motif. 
Pfam
 PF02815; MIR
 PF02366; PMT 
SMART
 SM00472; MIR 
PROSITE
 PS50919; MIR 
PRINTS