CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007937
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Calretinin 
Protein Synonyms/Alias
 CR 
Gene Name
 Calb2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
141GFLSDLLKKANRPYDacetylation[1]
151NRPYDEPKLQEYTQTacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Calretinin is a calcium-binding protein which is abundant in auditory neurons. 
Sequence Annotation
 DOMAIN 16 51 EF-hand 1.
 DOMAIN 63 98 EF-hand 2.
 DOMAIN 107 142 EF-hand 3.
 DOMAIN 151 186 EF-hand 4.
 DOMAIN 195 230 EF-hand 5.
 DOMAIN 235 270 EF-hand 6.  
Keyword
 Calcium; Complete proteome; Direct protein sequencing; Metal-binding; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 271 AA 
Protein Sequence
MAGPQQQPPY LHLAELTASQ FLEIWKHFDA DGNGYIEGKE LENFFQELEK ARKGSGMMSK 60
SDNFGEKMKE FMQKYDKNSD GKIEMAELAQ ILPTEENFLL CFRQHVGSSA EFMEAWRKYD 120
TDRSGYIEAN ELKGFLSDLL KKANRPYDEP KLQEYTQTIL RMFDLNGDGK LGLSEMSRLL 180
PVQENFLLKF QGMKLTSEEF NAIFTFYDKD GSGYIDENEL DALLKDLYEK NKKEMNIQQL 240
TTYRKSVMSL AEAGKLYRKD LEIVLCSEPP M 271 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:RGD.
 GO:0005921; C:gap junction; IEA:Compara.
 GO:0005634; C:nucleus; IDA:RGD.
 GO:0005509; F:calcium ion binding; IDA:RGD.
 GO:0051480; P:cytosolic calcium ion homeostasis; IDA:RGD. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 
Pfam
 PF13405; EF_hand_4
 PF13499; EF_hand_5 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS