| Tag | Content |
|---|
| CPLM ID | CPLM-016701 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Prolyl endopeptidase-like |
Protein Synonyms/Alias | Prolylendopeptidase-like |
Gene Name | Prepl |
Gene Synonyms/Alias | Kiaa0436 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 93 | ENMDAFEKVRTRLET | ubiquitination | [1] | | 131 | GCCLVRSKDEEADSD | ubiquitination | [1] | | 424 | TYKFAEGKLFEETGH | ubiquitination | [1] | | 437 | GHEDPITKTSRVLRI | ubiquitination | [1] | | 720 | TDAFEALKKYLKF** | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Probable serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue (By similarity). |
Sequence Annotation | ACT_SITE 557 557 Charge relay system (By similarity).
ACT_SITE 643 643 Charge relay system (By similarity).
ACT_SITE 688 688 Charge relay system (By similarity). |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Hydrolase; Protease; Reference proteome; Serine protease. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 725 AA |
Protein Sequence | MLQTAKFSLR ALKHSIPHLG NCMQKQSYRN VAGPYYSRVR LKKYHLTKCL QNKPRIAGLA 60
RNIPSRSFSC KDLLPIKPES EKPISENMDA FEKVRTRLET QPQEEYEVVN AEIKHGGFVY 120
YQEGCCLVRS KDEEADSDNY EVLFNLEELK LDQPFIDCIR VAPDEKYVAA KIRTEDSETS 180
TLVVVKLSDQ PVMEASFPNV SSFEWVKDEE DEDVLFYTFQ RNLRCHDVYR ATFGDNKRNE 240
RFYTEKDPSY FVFLYLTKDS RFLTLNIMNK TTSEVWLIDG LSPWDPPVLI QKRIHGMLYY 300
VEHRDDELYI LTNVGEPTEF KLMRTAADAP AIMNWDLFFT MKRNTKVVDL DMFKDHCVLF 360
LKHSNLLYVN VIGLADDSVR SLKLPPWACG FIMDTNSDPK NCPFQLCSPI RPPKYYTYKF 420
AEGKLFEETG HEDPITKTSR VLRIEAKSKD GKLVPMTVFH KTDSEDLQRK PLLVHVYGAY 480
GMDLKMNFRP EKRVLVDDGW ILAYCHVRGG GELGLQWHAD GRLTKKLNGL ADLVACIKTL 540
HSQGFSQPSL TTLSAFSAGG VLVGALCNSK PELLRAVTLE APFLDVLNTM LDTTLPLTLE 600
ELEEWGNPSS DEKHKNYIKR YCPCQNIKPQ HYPSVHITAY ENDERVPLKG IVNYTEKLKE 660
AVAEHTKGAG EGYQPPNIIL DIQPGGNHVI EDSHKKITTQ MKFLYEELGL DSTDAFEALK 720
KYLKF 725 |
Gene Ontology | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |