CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034825
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Mcm3 
Protein Synonyms/Alias
  
Gene Name
 Mcm3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
557DNLLHGSKKKREKMVacetylation[1]
661YFKKVLEKEKKRKKPacetylation[1]
663KKVLEKEKKRKKPSEacetylation[1]
699KRRKTQAKDGESYDPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; DNA replication; DNA-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 814 AA 
Protein Sequence
MAGTVVLDDV ELREAQRDYL DFLDDEEDQG IYQNKVRELI SDNQYRLIVN VNDLRRKNEK 60
RANRLLNNAF EELVAFQRAL KDFVASIDAT YAKQYEEFYI GLEGSFGSKH VSPRTLTSCF 120
LSCVVCVEGI VTKCSLVRPK VVRSVHYCPA TKKTIERRYS DLTTLVAFPS SSVYPTKDEE 180
NNPLETEYGL SVYKDHQTIT IQEMPEKAPA GQLPRSVDVI LDDDLVDKVK PGDRIQVVGT 240
YRCLPGKKGG YTSGTFRTVL IACNVKQMSK DIQPAFSADD IAKIKKFSKT RSKDVFEQLA 300
RSLAPSIHGH DYVKKAILCL LLGGVERELE NGSHIRGDIN ILLIGDPSVA KSQLLRYVLC 360
TAPRAIPTTG RGSSGVGLTA AVTTDQETGK GVGLPVRGLV LADRGVVCID EFDKMSDMDR 420
TAIHEVMEQG RVTIAKAGIH ARLNARCSVL AAANPVYGRY DQYKTPMENI GLQDSLLSRF 480
DLLFIMLDQM DPEQDREISD HVLRMHQYRA PGEQDGDALP LGSSVDILAT DDPDFTQDDQ 540
QDTRIYEKHD NLLHGSKKKR EKMVSAAFMK KYIHVAKIIK PTLTQESAAY IAEEYSRLRS 600
QDSMSSDTAR TSPVTARTLE TLIRLATAHA KARMSKTVDL QDAEEAVELV QYAYFKKVLE 660
KEKKRKKPSE DESDLEDEEE KSQEEDTEQT RKRRKTQAKD GESYDPYDFS EAEREMPQVH 720
TPKTDDSQEK TDESQETQES QKVELSESRL KAFKAALLEV FQEAHAQSVG MIHLTESINR 780
NKEEPFSSEE IQASLSRMQD DNQVMVSEGI VFLI 814 
Gene Ontology
 GO:0042555; C:MCM complex; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003678; F:DNA helicase activity; IEA:InterPro.
 GO:0032508; P:DNA duplex unwinding; IEA:GOC.
 GO:0006270; P:DNA replication initiation; IEA:InterPro. 
Interpro
 IPR008046; Mcm3.
 IPR018525; MCM_CS.
 IPR001208; MCM_DNA-dep_ATPase.
 IPR012340; NA-bd_OB-fold.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00493; MCM 
SMART
 SM00350; MCM 
PROSITE
 PS00847; MCM_1
 PS50051; MCM_2 
PRINTS
 PR01657; MCMFAMILY.
 PR01659; MCMPROTEIN3.