CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019002
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 566 
Protein Synonyms/Alias
  
Gene Name
 ZNF566 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
62ISYLEQGKEPWLADRubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 6 77 KRAB.
 ZN_FING 169 193 C2H2-type 1; degenerate.
 ZN_FING 199 221 C2H2-type 2.
 ZN_FING 227 249 C2H2-type 3.
 ZN_FING 255 277 C2H2-type 4.
 ZN_FING 283 395 C2H2-type 5.
 ZN_FING 311 333 C2H2-type 6.
 ZN_FING 339 361 C2H2-type 7.
 ZN_FING 367 389 C2H2-type 8.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 418 AA 
Protein Sequence
MAQESVMFSD VSVDFSQEEW ECLNDDQRDL YRDVMLENYS NLVSMGHSIS KPNVISYLEQ 60
GKEPWLADRE LTRGQWPVLE SRCETKKLFL KKEIYEIEST QWEIMEKLTR RDFQCSSFRD 120
DWECNRQFKK ELGSQGGHFN QLVFTHEDLP TLSHHPSFTL QQIINSKKKF CASKEYRKTF 180
RHGSQFATHE IIHTIEKPYE CKECGKSFRH PSRLTHHQKI HTGKKPFECK ECGKTFICGS 240
DLTRHHRIHT GEKPYECKEC GKAFSSGSNF TRHQRIHTGE KPYECKECGK AFSSGSNFTQ 300
HQRIHTGEKP YECKECGNAF SQSSQLIKHQ RIHTGEKPYE CKECEKAFRS GSDLTRHQRI 360
HTGEKPYECK ICGKAYSQSS QLISHHRIHT SEKPYEYREC GKNFNYDPQL IQHQNLYW 418 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS