CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029231
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Gamma-glutamyl carboxylase 
Protein Synonyms/Alias
 Gamma-glutymyl carboxylase; cDNA, FLJ93613, highly similar to Homo sapiens gamma-glutamyl carboxylase (GGCX), mRNA 
Gene Name
 GGCX 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
91GLSSLDRKYLDGLDVubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 758 AA 
Protein Sequence
MAVSAGSART SPSSDKVQKD KAELISGPRQ DSRIGKLLGF EWTDLSSWRR LVTLLNRPTD 60
PASLAVFRFL FGFLMVLDIP QERGLSSLDR KYLDGLDVCR FPLLDALRPL PLDWMYLVYT 120
IMFLGALGMM LGLCYRISCV LFLLPYWYVF LLDKTSWNNH SYLYGLLAFQ LTFMDANHYW 180
SVDGLLNAHR RNAHVPLWNY AVLRGQIFIV YFIAGVKKLD ADWVEGYSME YLSRHWLFSP 240
FKLLLSEELT SLLVVHWGGL LLDLSAGFLL FFDVSRSIGL FFVSYFHCMN SQLFSIGMFS 300
YVMLASSPLF CSPEWPRKLV SYCPQRLQQL LPLKAAPQPS VSCVYKRSRG KSGQKPGLRH 360
QLGAAFTLLY LLEQLFLPYS HFLTQGYNNW TNGLYGYSWD MMVHSRSHQH VKITYRDGRT 420
GELGYLNPGV FTQSRRWKDH ADMLKQYATC LSRLLPKYNV TEPQIYFDIW VSINDRFQQR 480
IFDPRVDIVQ AAWSPFQRTS WVQPLLMDLS PWRAKLQEIK SSLDNHTEVV FIADFPGLHL 540
ENFVSEDLGN TSIQLLQGEV TVELVAEQKN QTLREGEKMQ LPAGEYHKVY TTSPSPSCYM 600
YVYVNTTELA LEQDLAYLQE LKEKVENGSE TGPLPPELQP LLEGEVKGGP EPTPLVQTFL 660
RRQQRLQEIE RRRNTPFHER FFRFLLRKLY VFRRSFLMTC ISLRNLILGR PSLEQLAQEV 720
TYANLRPFEA VGELNPSNTD SSHSNPPESN PDPVHSEF 758 
Gene Ontology
 GO:0008488; F:gamma-glutamyl carboxylase activity; IEA:InterPro.
 GO:0017187; P:peptidyl-glutamic acid carboxylation; IEA:InterPro. 
Interpro
 IPR011020; HTTM.
 IPR014710; RmlC-like_jellyroll.
 IPR011051; RmlC_Cupin.
 IPR007782; VKG_COase. 
Pfam
 PF05090; VKG_Carbox 
SMART
 SM00752; HTTM 
PROSITE
  
PRINTS