CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014029
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein sel-1 homolog 2 
Protein Synonyms/Alias
 Suppressor of lin-12-like protein 2; Sel-1L2 
Gene Name
 SEL1L2 
Gene Synonyms/Alias
 C20orf50 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
101HLQKQAEKNFTDEGDubiquitination[1, 2]
Reference
 [1] Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry.
 Denis NJ, Vasilescu J, Lambert JP, Smith JC, Figeys D.
 Proteomics. 2007 Mar;7(6):868-74. [PMID: 17370265]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
  
Sequence Annotation
 REPEAT 107 142 Sel1-like 1.
 REPEAT 143 178 Sel1-like 2.
 REPEAT 179 214 Sel1-like 3.
 REPEAT 215 250 Sel1-like 4.
 REPEAT 297 333 Sel1-like 5.
 REPEAT 334 370 Sel1-like 6.
 REPEAT 371 406 Sel1-like 7.
 REPEAT 407 442 Sel1-like 8.
 REPEAT 443 478 Sel1-like 9.
 REPEAT 551 586 Sel1-like 10.
 REPEAT 588 623 Sel1-like 11.
 CARBOHYD 34 34 N-linked (GlcNAc...) (Potential).
 CROSSLNK 101 101 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Isopeptide bond; Membrane; Polymorphism; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 688 AA 
Protein Sequence
MKPLSLLIEI LIILGVTIKT IKAEEHNKRQ KERNVTTQVS VNEIKQYLSH ILEQRTSSNV 60
INKRENLLEK KKNQRKIRIK GIQNKDILKR NKNHLQKQAE KNFTDEGDQL FKMGIKVLQQ 120
SKSQKQKEEA YLLFAKAADM GNLKAMEKMA DALLFGNFGV QNITAAIQLY ESLAKEGSCK 180
AQNALGFLSS YGIGMEYDQA KALIYYTFGS AGGNMMSQMI LGYRYLSGIN VLQNCEVALS 240
YYKKVADYIA DTFEKSEGVP VEKVRLTERP ENLSSNSEIL DWDIYQYYKF LAERGDVQIQ 300
VSLGQLHLIG RKGLDQDYYK ALHYFLKAAK AGSANAMAFI GKMYLEGNAA VPQNNATAFK 360
YFSMAASKGN AIGLHGLGLL YFHGKGVPLN YAEALKYFQK AAEKGWPDAQ FQLGFMYYSG 420
SGIWKDYKLA FKYFYLASQS GQPLAIYYLA KMYATGTGVV RSCRTAVELY KGVCELGHWA 480
EKFLTAYFAY KDGDIDSSLV QYALLAEMGY EVAQSNSAFI LESKKANILE KEKMYPMALL 540
LWNRAAIQGN AFARVKIGDY HYYGYGTKKD YQTAATHYSI AANKYHNAQA MFNLAYMYEH 600
GLGITKDIHL ARRLYDMAAQ TSPDAHIPVL FAVMKLETTH LLRDILFFNF TTRWNWLKLD 660
NTIGPHWDLF VIGLIVPGLI LLLRNHHG 688 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR006597; Sel1-like.
 IPR011990; TPR-like_helical. 
Pfam
 PF08238; Sel1 
SMART
 SM00671; SEL1 
PROSITE
  
PRINTS