UniProt Accession

 H1_DROME; P02255; Q4ABD3 

Genbank Protein ID

 X04073; X14215; AE014134; AE014134; AE014134; AE014134; AE014134; AE014134; AE014134; AE014134; AE014134; AE014134; AE014134; AE014134; AE014134; AE014134; AE014134; AE014134; AE014134; X60225 

Genbank Nucleotide ID

 CAA27716.1; CAA32433.1; AAN11123.1; AAZ66482.1; AAZ66491.1; AAZ66495.1; AAZ66500.1; AAZ66505.1; AAZ66510.1; AAZ66515.1; AAZ66520.1; AAZ66525.1; AAZ66535.1; AAZ66540.1; AAZ66545.1; AAZ66555.1; AAZ66550.1; AAZ66560.1; AAZ66580.1; CAA42786.1 

Protein Name

 Histone H1 

Protein Synonyms/Alias

  

Gene Name

 His1; His1:CG31617; His1:CG33804; His1:CG33810; His1:CG33813; His1:CG33816; His1:CG33819; His1:CG33822; His1:CG33825; His1:CG33828; His1:CG33831; His1:CG33837; His1:CG33840; His1:CG33843; His1:CG33846; His1:CG33849; His1:CG33852; His1:CG33864 

Gene Synonyms/Alias

 CG31617; CG33804; CG33810; CG33813; CG33816; CG33819; CG33822; CG33825; CG33828; CG33831; CG33837; CG33840; CG33843; CG33846; CG33849; CG33852; CG33864 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
22	APPATVEKKVVQKKA	acetylation	[1]
95	PFIKKYLKSAVVNGK	acetylation	[1]
102	KSAVVNGKLIQTKGK	acetylation	[1]
164	TAVGAADKKPKAKKA	acetylation	[2]
250	TAKKPKAKTTAAKK*	acetylation	[2]
255	KAKTTAAKK******	acetylation	[2]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702]
 [2] Combined bottom-up and top-down mass spectrometry analyses of the pattern of post-translational modifications of Drosophila melanogaster linker histone H1.
 Bonet-Costa C, Vilaseca M, Diema C, Vujatovic O, Vaquero A, Omeñaca N, Castejón L, Bernués J, Giralt E, Azorín F.
 J Proteomics. 2012 Jul 16;75(13):4124-38. [PMID: 22647927] 

Functional Description

 Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. 

Sequence Annotation

 DOMAIN 45 119 H15.
 MOD_RES 11 11 Phosphoserine.  

Keyword

 Chromosome; Complete proteome; Direct protein sequencing; DNA-binding; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 256 AA 

Protein Sequence

Gene Ontology

 GO:0000786; C:nucleosome; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 

Interpro

 IPR005818; Histone_H1/H5.
 IPR005819; Histone_H5.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00538; Linker_histone 

SMART

 SM00526; H15 

PROSITE

 PS51504; H15 

PRINTS

 PR00624; HISTONEH5.