UniProt Accession

 MTFP1_MOUSE; Q9CRB8; Q9CZX4 

Genbank Protein ID

 AK006148; AK010971; AK012058; AK078381; BC058737 

Genbank Nucleotide ID

 BAB24432.1; BAB27300.1; BAB27999.1; BAC37244.1; AAH58737.1 

Protein Name

 Mitochondrial fission process protein 1 

Protein Synonyms/Alias

 Mitochondrial 18 kDa protein; MTP18 

Gene Name

 Mtfp1 

Gene Synonyms/Alias

 Mtp18 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
123	HWPPTVRKWTTTTLG	acetylation	[1]
123	HWPPTVRKWTTTTLG	succinylation	[1]

Reference

 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

 Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function leads to apoptosis (By similarity). 

Sequence Annotation

  

Keyword

 Apoptosis; Complete proteome; Direct protein sequencing; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 166 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.
 GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
 GO:0000266; P:mitochondrial fission; ISS:UniProtKB.
 GO:0007006; P:mitochondrial membrane organization; ISA:MGI. 

Interpro

 IPR019560; Mitochondrial_18_kDa_protein_. 

Pfam

 PF10558; MTP18 

SMART

  

PROSITE

  

PRINTS