Tag | Content |
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CPLM ID | CPLM-016130 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vacuolar protein sorting-associated protein 37D |
Protein Synonyms/Alias | ESCRT-I complex subunit VPS37D; Williams-Beuren syndrome region protein 24 homolog |
Gene Name | Vps37d |
Gene Synonyms/Alias | Wbscr24 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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85 | GRTALAIKYQELREV | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation (By similarity). |
Sequence Annotation | DOMAIN 93 182 VPS37 C-terminal. |
Keyword | Alternative splicing; Complete proteome; Endosome; Membrane; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 261 AA |
Protein Sequence | MYRARAARAG PEPGSPGRFG ILSTGQLRDL LQDEPKLDRI VRLSRKFQGL QLERDACLAS 60 NYALAKENLA LRPRLEMGRT ALAIKYQELR EVAENCADKL QRLEKSMHRW SPQCALGWLQ 120 AELEEAEQEA EVQMEQLLLG EQSLEAFLPA FQRGRALAHL RRTQAEKLQE VLRRRERSAQ 180 PAPTTAAAAA AAATAMDPPK PFPAAAVLPT GAARGPPPAV PRSLPPLDSR PVPPVKGSPG 240 CPFGPAPLLS PRPSQPEPPH R 261 |
Gene Ontology | GO:0000813; C:ESCRT I complex; ISS:UniProtKB. GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell. GO:0015031; P:protein transport; IEA:UniProtKB-KW. |
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Pfam | |
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PROSITE | |
PRINTS | |