CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016130
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vacuolar protein sorting-associated protein 37D 
Protein Synonyms/Alias
 ESCRT-I complex subunit VPS37D; Williams-Beuren syndrome region protein 24 homolog 
Gene Name
 Vps37d 
Gene Synonyms/Alias
 Wbscr24 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
85GRTALAIKYQELREVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation (By similarity). 
Sequence Annotation
 DOMAIN 93 182 VPS37 C-terminal.  
Keyword
 Alternative splicing; Complete proteome; Endosome; Membrane; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 261 AA 
Protein Sequence
MYRARAARAG PEPGSPGRFG ILSTGQLRDL LQDEPKLDRI VRLSRKFQGL QLERDACLAS 60
NYALAKENLA LRPRLEMGRT ALAIKYQELR EVAENCADKL QRLEKSMHRW SPQCALGWLQ 120
AELEEAEQEA EVQMEQLLLG EQSLEAFLPA FQRGRALAHL RRTQAEKLQE VLRRRERSAQ 180
PAPTTAAAAA AAATAMDPPK PFPAAAVLPT GAARGPPPAV PRSLPPLDSR PVPPVKGSPG 240
CPFGPAPLLS PRPSQPEPPH R 261 
Gene Ontology
 GO:0000813; C:ESCRT I complex; ISS:UniProtKB.
 GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR009851; Mod_r. 
Pfam
 PF07200; Mod_r 
SMART
  
PROSITE
 PS51314; VPS37_C 
PRINTS