CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041271
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kelch repeat and BTB (POZ) domain containing 3, isoform CRA_a 
Protein Synonyms/Alias
 Kelch repeat and BTB domain-containing protein 3 
Gene Name
 KBTBD3 
Gene Synonyms/Alias
 hCG_40528 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
340TRGSRDIKSLLDVESubiquitination[1]
353ESYNPLSKEWISVSPubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kelch repeat; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 533 AA 
Protein Sequence
MFEVNMKERD DGSVTITNLS SKAVKAFLDY AYTGKTKITD DNVEMFFQLS SFLQVSFLSK 60
ACSDFLIKSI NLVNCLQLLS ISDSYGSTSL FDHALHFVQH HFSLLFKSSD FLEMNFGVLQ 120
KCLESDELNV PEEEMVLKVV LSWTKHNLES RQKYLPHLIE KVRLHQLSEE TLQDCLFNEE 180
SLLKSTNCFD IIMDAIKCVQ GSGGLFPDAR PSTTEKYIFI HKTEENGENQ YTFCYNIKSD 240
SWKILPQSHL IDLPGSSLSS YGEKIFLTGG CKGKCCRTVR LHIAESYHDA TDQTWCYCPV 300
KNDFFLVSTM KTPRTMHTSV MALDRLFVIG GKTRGSRDIK SLLDVESYNP LSKEWISVSP 360
LPRGIYYPEA STCQNVIYVL GSEVEITDAF NPSLDCFFKY NATTDQWSEL VAEFGQFFHA 420
TLIKAVPVNC TLYICDLSTY KVYSFCPDTC VWKGEGSFEC AGFNAGAIGI EDKIYILGGD 480
YAPDEITDEV QVYHSNRSEW EEVSPMPRAL TEFYCQVIQF NKYRDPWFSN LCA 533 
Gene Ontology
  
Interpro
 IPR011705; BACK.
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR013069; BTB_POZ.
 IPR015915; Kelch-typ_b-propeller.
 IPR006652; Kelch_1. 
Pfam
 PF07707; BACK
 PF00651; BTB
 PF01344; Kelch_1 
SMART
 SM00875; BACK
 SM00612; Kelch 
PROSITE
 PS50097; BTB 
PRINTS