UniProt Accession

 E9Q805_MOUSE; E9Q805 

Genbank Protein ID

 AC154618; AC165163; AC167566 

Genbank Nucleotide ID

  

Protein Name

 FERM, RhoGEF and pleckstrin domain-containing protein 1 

Protein Synonyms/Alias

  

Gene Name

 Farp1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
141	YLFALQVKQDLAQGR	ubiquitination	[1]
184	REHLAKNKYVPQQDA	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 211 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005856; C:cytoskeleton; IEA:InterPro.
 GO:0019898; C:extrinsic to membrane; IEA:InterPro.
 GO:0010923; P:negative regulation of phosphatase activity; IEA:Compara. 

Interpro

 IPR019749; Band_41_domain.
 IPR019750; Band_41_fam.
 IPR000798; Ez/rad/moesin_like.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
 IPR019748; FERM_central.
 IPR019747; FERM_CS.
 IPR000299; FERM_domain.
 IPR018979; FERM_N. 

Pfam

 PF00373; FERM_M
 PF09379; FERM_N 

SMART

 SM00295; B41 

PROSITE

 PS00660; FERM_1
 PS50057; FERM_3 

PRINTS

 PR00935; BAND41.
 PR00661; ERMFAMILY.