UniProt Accession

 B4E3J8_HUMAN; B4E3J8 

Genbank Protein ID

 AC092827; AC092829; AK304755 

Genbank Nucleotide ID

 BAG65510.1 

Protein Name

 Serine/threonine-protein kinase 38-like 

Protein Synonyms/Alias

 cDNA FLJ50384, highly similar to Serine/threonine-protein kinase 38-like (EC 2.7.11.1) 

Gene Name

 STK38L 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
17	EVRLVQKKDTGHIYA	ubiquitination	[1]
26	TGHIYAMKILRKSDM	ubiquitination	[1]
122	GFIHRDIKPDNLLLD	ubiquitination	[2]
131	DNLLLDAKGHVKLSD	ubiquitination	[2]
135	LDAKGHVKLSDFGLC	ubiquitination	[1]
146	FGLCTGLKKAHRTEF	ubiquitination	[1]
147	GLCTGLKKAHRTEFY	ubiquitination	[1]
173	SFQNMNSKRKAETWK	ubiquitination	[1]
285	NSGVEEIKGHPFFEG	ubiquitination	[1]
367	GSIPTYMKAGKL***	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 371 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0005886; C:plasma membrane; IDA:HPA.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. 

Interpro

 IPR000961; AGC-kinase_C.
 IPR011009; Kinase-like_dom.
 IPR017892; Pkinase_C.
 IPR000719; Prot_kinase_cat_dom.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 

Pfam

 PF00069; Pkinase
 PF00433; Pkinase_C 

SMART

 SM00133; S_TK_X
 SM00220; S_TKc 

PROSITE

 PS51285; AGC_KINASE_CTER
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 

PRINTS