CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032753
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Histone acetyltransferase GCN5, putative 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_103310 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
857PRAGADGKGISEAERacetylation[1, 2]
989TPKIQALKQAFQQQQacetylation[1, 2]
997QAFQQQQKQLAQKGAacetylation[1, 2]
1027DEGLVGAKHPTFF**acetylation[1, 2]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907]
 [2] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842] 
Functional Description
  
Sequence Annotation
  
Keyword
 Acyltransferase; Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1032 AA 
Protein Sequence
MAPSECPSDA PGGSGESRVS AEPSSSETPS SAVSSHSPHR AQLSSTQPKN PASPPTSDIS 60
APHVPLLGAE ASGGDPSADP LGGEGAMERE RQAFAEGPGL SARVETALSP QLRTTSGELQ 120
QAAADAAVSP DGEKEKEVAN SRKGEDSGRL SAFVGRGSRR SSHAEPAEGP SLPSGADGRL 180
PASGPWASEA PPAGRSASAP VPPVSPGFAF PSVTSCLPLN ASIGDIALRL VKEILQPVLA 240
RDIQVDPPSP FRFTASGMAK ALELSPVCFS PAYAASLRKS YAQMGTAGSC FYCVSAPCVC 300
GAFAPPLAQA RPAENKKRGR DACEGPQAEP PVGRGPRRGP NDSGAPVGQD LPGGPQAPGG 360
PGGGFGAGQT FQDNLRQMCL FHPYSSVPPP KLIDMRYLCL FLSASADSPF ACATRTGLCP 420
FFGDGPFGPD GETRNGREGP LARSGDKVEG EKTFLSFVDE TADFGDASVE KGFPDHARIG 480
WEVVEEVAES LEAIFNTIQM ETVEDRRDAL TVPDEFYAQN YWEWRQFLLD KAPTGASVSR 540
TFGRSLLRSL LLASPGTIAK DLQRTPISFA AGILFFRLCE EVGIEPETRH VLWRTVASSQ 600
PELRSRLVSE SGLGFLCRDL GSAKEEEAGL ITFKCVTNDR QPFSSRALVT VKNIFSRQLP 660
KMPREYIVRL VFDRNHYTFC LNKEDTIIGG CCFRPYFQQK FAEIAFLAVT STEQVKGYGT 720
RLMNHLKEHV KKSGIEYFLT YADNFAVGYF RKQGFTQKIS MPRERWYGYI KDYEGGTLME 780
CHINPRINYL RLSEMLHDQQ QVIKRATVSL KPLAVYPGLD FWKKNPGQTL SPSQIPGLLQ 840
CGWHPGEGAP RAGADGKGIS EAERAFLGST GAPDGAGSAG VGQGYMRPLH EQIMDILDAL 900
GKHHSAWPFL KPVSREEAPD YYDVILQPTD ISTMKKKCKK KHYTTAQMFA DEVQLMFKNC 960
RQYNHQQTIY YKYANELDKF VTPKIQALKQ AFQQQQKQLA QKGAASGTGV PPLRSPQGGD 1020
EGLVGAKHPT FF 1032 
Gene Ontology
 GO:0004402; F:histone acetyltransferase activity; IEA:EC.
 GO:0016573; P:histone acetylation; IEA:GOC. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR001487; Bromodomain.
 IPR000182; GNAT_dom. 
Pfam
 PF13508; Acetyltransf_7
 PF00439; Bromodomain 
SMART
 SM00297; BROMO 
PROSITE
 PS50014; BROMODOMAIN_2
 PS51186; GNAT 
PRINTS
 PR00503; BROMODOMAIN.